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Clinical Autonomic Dysfunction pp 115–123Cite as

Cardiovascular Autonomic Neuropathy: Risk Factor or Risk Indicator

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Abstract

This chapter discusses some more recent articles regarding risk factors and inflammation. There is a significant body of evidence that associates cardiovascular autonomic neuropathy (CAN) with most risk factors and with inflammation. It is known that CAN is associated with increased morbidity and mortality risk. The associations with traditional and nontraditional, as well as modifiable and nonmodifiable, risk factors, including inflammation, have historically made CAN a difficult diagnosis, especially since the perception has been that CAN is not treatable. This chapter concludes by explaining that this perception is not correct and discusses, generally, possible treatment modalities. Within the community of P&S monitoring, CAN has become an important diagnosis to document as early as possible to help avoid increased morbidity and mortality risk that leads to greater medication loads and hospitalization rates, causing greater healthcare costs.

Keywords

  • Sudden Cardiac Death
  • Autonomic Dysfunction
  • Autonomic Neuropathy
  • Parasympathetic Activity
  • Cardiovascular Autonomic Neuropathy

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Authors and Affiliations

  1. Autonomic Laboratory Department of Cardiology, Drexel University College of Medicine, Philadelphia, PA, USA

    Joseph Colombo PhD

  2. ANSAR Medical Technologies, Inc., Philadelphia, PA, USA

    Joseph Colombo PhD

  3. Department of Medicine, Captain James A. Lovell Federal Health Care Center, North Chicago, IL, USA

    Rohit Arora MD, FACC, FAHA, FACP, FSCAI

  4. Department of Cardiology, The Chicago Medical School, North Chicago, IL, USA

    Rohit Arora MD, FACC, FAHA, FACP, FSCAI

  5. Department of Cardiology, Hahnemann Hospital Drexel University College of Medicine, Philadelphia, PA, USA

    Nicholas L. DePace MD, FACC

  6. Department of Medicine, Eastern Virginia Medical School Strelitz Diabetes Research Center, Norfolk, VA, USA

    Aaron I. Vinik MD, PhD, FCP, MACP

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  3. Nicholas L. DePace MD, FACC
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Colombo, J., Arora, R., DePace, N.L., Vinik, A.I. (2015). Cardiovascular Autonomic Neuropathy: Risk Factor or Risk Indicator. In: Clinical Autonomic Dysfunction. Springer, Cham. https://doi.org/10.1007/978-3-319-07371-2_9

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