Abstract
Description of the drug: Cylindrical or semicylindrical, 5–10 cm long, 0.5–5 cm in diameter. Externally yellowish-brown to greyish brown, with distinct wrinkles, longitudinal furrows and lateral root scars. Texture hard, uneasily broken, fracture greyish-brown to dark brown, the outer layer greyish-yellow or brownish-yellow, cambium ring brown, having radial lines and scattered brown dotted oil cavities. Odour, characteristic and aromatic; taste, slightly bitter.
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References
Pharmacopoeia of the People’s Republic of China, English Edition, vol. 1. People’s Medical Publishing House, Beijing (2010)
Paulus, E., Ding, Y.-H.: Handbuch der traditionellen chinesischen Heilpflanzen. Karl F. Haug Verlag, Heidelberg (1987)
Hempen, C.H., Fischer, T., A materia medica for Chinese medicine: plants, minerals and animal products, 1st Edition Churchill Livingstone Elsevier, New York (2009)
Tang, W., Eisenbrand, G.: Handbook of Chinese medicinal plants, vol. 1. Wiley-VCH Verlag, Weinheim (2011)
Stöger, E.A.: Arzneibuch der chinesischen Medizin. Dtsch. Apoth.- Verlag, Stuttgart (2001)
Hong Kong Chinese materia medica standards, vol. 2, Chinese Medicine Division – Department of Health – Government of the Hong Kong Special Administrative Region. Hong Kong (2008)
Tan, R.X., Jakupovic, J., Jia, Z.J.: Aromatic Constituents from Vladimiria Souliei. Planta Med. 56(5), 475–477 (1990)
Chen, H.C., Chou, C.K., Lea, S.D., Yeh, S.F.: Active compounds from Saussurea lappa Clarks that suppress hepatitis B virus surface antigen gene expression in human hepatoma cells. Antiviral Res. 27(1–2), 99–109 (1995)
Sun, C.M., Syu, W.J., Don, M.J., Lu, J.J., Lee, G.H.: Cytotoxic sesquiterpene lactones from the root of Saussurea lappa. J. Nat. Prod. 66(9), 1175–1180 (2003)
Damre, A.A., Damre, A.S., Saraf, M.N.: Evaluation of sesquiterpene lactone fraction of Saussurea lappa on transudative, exudative and proliferative phases of inflammation. Phytother. Res. 17(7), 722–725 (2003)
Lee, M.G., Lee, K.T., Chi, S.G., Park, J.H.: Costunolide induces apoptosis by ROS-mediated mitochondrial permeability transition and cytochrome C release. Biol. Pharm. Bull. 24(3), 303–306 (2001)
Chun, J., Choi, R.J., Khan, S., Lee, D.S., Kim, Y.C., Nam, Y.J., Lee, D.U., Kim, Y.S.: Alantolactone suppresses inducible nitric oxide synthase and cyclooxygenase-2 expression by down-regulating NF-κB, MAPK and AP-1 via the MyD88 signaling pathway in LPS-activated RAW 264.7 cells. Int. Immunopharmacol. 14(4), 375–383 (2012)
Choi, H.G., Lee, D.S., Li, B., Choi, Y.H., Lee, S.H., Kim, Y.C.: Santamarin, a sesquiterpene lactone isolated from Saussurea lappa, represses LPS-induced inflammatory responses via expression of heme oxygenase-1 in murine macrophage cells. Int. Immunopharmacol. 13(3), 271–279 (2012)
Yun, Y.G., Oh, H., Oh, G.S., Pae, H.O., Choi, B.M., Kwon, J.W., Kwon, T.O., Jang, S.I., Chung, H.T.: In vitro cytotoxicity of Mokko lactone in human leukemia HL-60 cells: induction of apoptotic cell death by mitochondrial membrane potential collapse. Immunopharmacol. Immunotoxicol. 26(3), 343–353 (2004)
Choi, J.Y., Choi, E.H., Jung, H.W., Oh, J.S., Lee, W.H., Lee, J.G., Son, J.K., Kim, Y., Lee, S.H.: Melanogenesis inhibitory compounds from Saussureae Radix. Arch. Pharm. Res. 31(3), 294–299 (2008)
Zhang, T., Wang, H., Du, G., Chen, R.: Study on chemical constituents from roots of Saussurea lappa. Zhongguo. Zhong. Yao. Za. Zhi. 34(10), 1223–1224 (2009)
Robinson, A., Kumar, T.V., Sreedhar, E., Naidu, V.G., Krishna, S.R., Babu, K.S., Srinivas, P.V., Rao, J.M.: A new sesquiterpene lactone from the roots of Saussurea lappa: structure-anticancer activity study. Bioorg. Med. Chem. Lett. 18(14), 4015–4017 (2008)
Zhang, T., Ma, L., Wu, F., Chen, R.: Chemical constituents from a portion of ethanolic extract of Saussurea lappa roots. Zhongguo. Zhong. Yao. Za. Zhi. 37(9), 1232–1236 (2012)
Duan, J.A., Hou, P., Yang, Y., Liu, P., Su, S., Liu, H.: A new sesquiterpene and other constituents from Saussurea lappa root. Nat. Prod. Commun. 5(10), 1531–1534 (2010)
Choi, J.Y., Na, M.K., Hwang, I.H., Lee, S.H., Bae, E.Y., Kim, B.Y., Ahn, J.S.: Isolation of betulinic acid, its methyl ester and guaiane sesquiterpenoids with proteine thyrosine phosphatase 1B inhibitory activity from the roots of Saussurea lappa C.B.Clarke. Molecules 14(1), 266–272 (2009)
Yoshikawa, M., Hatakeyama, S., Inoue, Y., Yamahara, J., Saussureamins, A.: B, C, D, and E, new anti-ulcer principles from Chinese Saussureae Radix. Chem. Pharm. Bull. 42(1), 214–216 (1993)
Chen, F., Chan, H.Y., Wong, K.L., Wang, J., Yu, M.T., But, P.P., Shaw, P.C.: Authentication of Saussurea lappa, an endangered medicinal material, by ITS DNA and 5S rRNA sequencing. Planta Med. 74(8), 889–892 (2008)
Wagner, H., Bauer, R., Melchart, D., Pei-Gen Xiao, A. (eds.): Chromatographic Fingerprint Analysis of Herbal Medicines, vol. I, pp. 311–324. Staudinger, Springer, Wien/New York (2011)
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Wagner, H., Bauer, R., Melchart, D., Xiao, PG., Staudinger, A. (2015). Radix Aucklandiae – Muxiang . In: Wagner, H., Bauer, R., Melchart, D., Xiao, PG., Staudinger, A. (eds) Chromatographic Fingerprint Analysis of Herbal Medicines Volume III. Springer, Cham. https://doi.org/10.1007/978-3-319-06047-7_22
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DOI: https://doi.org/10.1007/978-3-319-06047-7_22
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