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Ovulation Induction and Controlled Ovarian Stimulation pp 121–128Cite as

Gonadotrophins for Ovulation Induction

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Abstract

The availability of injectable gonadotrophin preparations provides a direct route for ovarian stimulation and ovulation induction as opposed to the indirect route of provoking endogenous FSH release taken by clomifene and letrozole. As far as the outcome of treatment for anovulation is concerned, no clear clinical superiority has been demonstrated between urinary and recombinant products nor between hMG and pure FSH. Recombinant products are purer and therefore, theoretically at least, safer than urinary products. The one group of patients in which the addition of LH seems to be critical is that of women with hypogonadotrophic-hypogonadism who have no endogenous LH. These women need exogenous hCG or recombinant LH to maintain adequate oestradiol biosynthesis and follicle development.

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Authors and Affiliations

  1. Homerton Fertility Centre, Homerton University Hospital, London, UK

    Roy Homburg

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  1. Roy Homburg
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© 2014 Springer International Publishing Switzerland

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Homburg, R. (2014). Gonadotrophins for Ovulation Induction. In: Ovulation Induction and Controlled Ovarian Stimulation. Springer, Cham. https://doi.org/10.1007/978-3-319-05612-8_13

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  • DOI: https://doi.org/10.1007/978-3-319-05612-8_13

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-05611-1

  • Online ISBN: 978-3-319-05612-8

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