Abstract
Toxic epidermal necrolysis (TEN) is a diagnostic emergency. Management of this disease should take place in a specialised centre. The usual causative drugs in children are sulphonamide antibiotics, antiepileptics and non-steroidal anti-inflammatory drugs. Causative drugs should be stopped definitively and as quickly as possible. Treatment consists essentially of hydroelectrolytic replacement, nutritional support, analgesia and use of sterile dressings. Systemic immunosuppressive treatments and plasmapheresis may be used. Treatment of mucosal attacks (oral, ocular and genital in particular) is essential to limit long-term sequellae. Psychological support should also be considered.
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Michel, F. (2014). Toxic Epidermal Necrolysis in Children. In: Leone, M., Martin, C., Vincent, JL. (eds) Uncommon Diseases in the ICU. Springer, Cham. https://doi.org/10.1007/978-3-319-04576-4_17
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DOI: https://doi.org/10.1007/978-3-319-04576-4_17
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