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Biotechnology of Nutritionally Enhanced Food Crops Targeting Malnutrition in Rural Agricultural Populations: The Case Study of Africa Biofortified Sorghum

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Biotechnology in Africa

Part of the book series: Science Policy Reports ((SCIPOLICY,volume 7))

Abstract

Biofortification of staple foods has great potential in alleviating the rampant micronutrient deficiency in low income countries, mainly in Africa, through developing staple foods with enhanced minerals and vitamins. The three most important minerals and vitamins of focus include enhanced vitamin A and bioavailable zinc and iron, while folate and iodine deficiencies are met through other approaches including fortification. Currently, on-going research in biotransformation focuses on developing four staples (rice, sorghum, cassava, and bananas) with enhanced pro-vitamin A, zinc, and iron. Of these, Africa biofortified sorghum, cassava, and bananas mainly target African countries. In the Africa Biofortified Sorghum Project, the first priority product to be commercialized will be sorghum with enhanced vitamin A, and the second priority product will be to augment pro-vitamin A with increased bioavailable zinc and iron. The primary target countries of release will be Kenya and Nigeria, representing East Africa, and West Africa Anglophone countries, respectively. Biofortification through genetic transformation complements on-going biofortification efforts through conventional breeding and fortification, especially among those rural farmers/consumers that do not buy commercial fortified foods, or consumers located in arid and semi-arid regions of Africa with little access to vegetables and fruits in the dry seasons.

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Abbreviations

AATF:

African Agricultural Technology Foundation

ABS:

Africa Biofortified Sorghum

AHBFI:

Africa Harvest Biotechnology Foundation International

ARC:

Agricultural Research Council (South Africa)

ARIPO:

African Regional Intellectual Property Organization

CFT:

Confined field trial

CNP:

Candidate novel protein

CORAF/WECARD:

West and Central Council for Agriculture Research and Development

CRT I:

Carotene desaturase I

CSIR:

Council of Scientific and Industrial Research (South Africa)

DALY:

Disability‐adjusted life year

FTO:

Freedom to operate

GCGH:

Grand Challenge for Global Health

GI:

Gastrointestinal

IAR:

Institute of Agricultural Research (Nigeria)

ICRISAT:

International Crops Research Institute for the Semi-Arid Tropics

INERA:

Institut de l’Environnement et de Recherches Agricoles (Burkina Faso)

IPMT:

Intellectual Property Management Team

KARI:

Kenya Agricultural Research Institute

MAB:

Marker assisted breeding

NABDA:

National Biotechnology Development Agency (Nigeria)

NARS:

National agricultural research system

NBA:

National Biosafety Authority

NGO:

Non-governmental organization

OAPI:

Organisation Africaine de la Propriété intellectuelle

OPVS:

Open-pollinated varieties

PMI:

Phosphomannoseisomerase

PSY1:

Phytoene synthase

SADC:

Southern African Development Community

SGF:

Simulated mammalian gastric fluid

VAD:

Vitamin A deficiency

YLD:

Years lived with disability

YLL:

Years of life lost

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Acknowledgements

This is to thank the ABS Consortium Members and institutions for their invaluable contribution to the achievements of the Project. We are grateful to the Bill and Melinda Gates Foundation for funding ABS Phase I, and the on-going Howard Buffet Foundation funding of ABS Phase II. Our gratitude is also extended to the institutions that DONATED (not gave) ABS IP rights, including Syngenta, DuPont Pioneer, Japan Tobacco, and Freiburg University in Germany/Syngenta.

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Correspondence to Silas D. Obukosia .

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Obukosia, S.D. (2014). Biotechnology of Nutritionally Enhanced Food Crops Targeting Malnutrition in Rural Agricultural Populations: The Case Study of Africa Biofortified Sorghum. In: Wambugu, F., Kamanga, D. (eds) Biotechnology in Africa. Science Policy Reports, vol 7. Springer, Cham. https://doi.org/10.1007/978-3-319-04001-1_9

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