Abstract
Also known as the Friedländer condensation, it combines an α-amino aldehyde or ketone with another aldehyde or ketone with at least one methylene α adjacent to the carbonyl to furnish a substituted quinoline. The reaction can be promoted by either acid, base, or heat.
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References
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Li, J.J. (2014). Friedländer quinoline synthesis. In: Name Reactions. Springer, Cham. https://doi.org/10.1007/978-3-319-03979-4_110
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DOI: https://doi.org/10.1007/978-3-319-03979-4_110
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