Abstract
Acute respiratory distress syndrome (ARDS) is a life-threatening form of acute respiratory failure characterized by acute hypoxemia and by diffuse pulmonary infiltrates on chest radiography. ARDS represents a common pathway of lung injury that arises in a variety of clinical settings, most often associated with pneumonia, sepsis, and trauma. Many treatments have been explored in ARDS, but most success has come through avoidance of iatrogenic ventilator-associated lung injury by manipulation of the mechanical ventilator. Using conventional ventilation, we now know that strategies that limit tidal volumes and inspiratory pressures, and which employ higher levels of positive end-expiratory pressure (PEEP) lead to significant reductions in mortality [1, 2]. In recent years there has been an increasing interest in non-conventional modes of ventilation. In this chapter, we review several of these ‘new’ modes and discuss their applicability to the patient with ARDS.
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References
The Acute Respiratory Distress Syndrome Network (2000) Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 342:1301–1308
Briel M, Meade M, Mercat A et al (2010) Higher vs lower positive end-expiratory pressure in patients with acute lung injury and acute respiratory distress syndrome: systematic review and meta-analysis. JAMA 303:865–873
Guldager H, Nielsen SL, Carl P et al (1997) A comparison of volume control and pressure-regulated volume control ventilation in acute respiratory failure. Crit Care 1:75–77
Riverso P, Bernardi PL, Corsa D et al (1998) A comparison of ventilation techniques in ARDS. Volume controlled vs pressure regulated volume control. Minerva Anestesiol 64:339–343
Lunkenheimer PP, Rafflenbeul W, Keller H et al (1972) Application of transtracheal pressure oscillations as a modification of “diffusion respiration”. Br J Anaesth 44:627
Bryan AC (2001) The oscillations of HFO. Am J Respir Crit Care Med 163:816–817
Derdak S, Mehta S, Stewart TE et al (2002) High-frequency oscillatory ventilation for acute respiratory distress syndrome in adults: a randomized, controlled trial. Am J Respir Crit Care Med 166:801–808
Sud S, Sud M, al Friedrichet JO (2010) High frequency oscillation in patients with acute lung injury and acute respiratory distress syndrome (ARDS): systematic review and meta-analysis. BMJ 340:1–11
Young D, Lamb SE, Shah S et al (2013) High-frequency oscillation for acute respiratory distress syndrome. N Engl J Med 368:806–813
Ferguson ND, Cook DJ, Guyatt GH et al (2013) High-frequency oscillation in early acute respiratory distress syndrome. N Engl J Med 10(368):795–805
Downs JB, Stock MC (1987) Airway pressure release ventilation: a new concept in ventilatory support. Crit Care Med 15:459–461
Gonzalez M, Arroliga A, Frutos-Vivar F, et al (2010) Airway pressure release ventilation versus assist-control ventilation: a comparative propensity score and international cohort study 36: 817–827
Putensen C, Zech S, Wrigge H et al (2001) Long term effects of spontaneous breathing during ventilatory support during ventilatory support in patients with acute lung injury. Am J Respir Crit Care Med 164:43–49
Varpula T, Valta P, Niemi R et al (2004) Airway pressure release ventilation as a primary ventilatory mode in acute respiratory distress syndrome. Acta Anaesthesiol Scand 48:722–731
Sinderby C, Navalesi P, Beck J et al (1999) Neural control of mechanical ventilation in respiratory failure. Nature Med 5:1433–1436
Levine S, Nguyen T, Taylor N et al (2008) Rapid disuse atrophy of diaphragmatic fibers in mechanically ventilated humans. N Engl J Med 358:1327–1335
Froese AB, Bryan C (1974) Effects of anesthesia and paralysis on diaphragmatic mechanics in man. Anesthesiology 41:242–255
Knisely AS, Leal SM, Singer DB (1988) Abnormalities of diaphragmatic muscle in neonates with ventilated lungs. J Pediatr 113:1074–1077
Thille AW, Cabello B, Galia F, Lyazidi A, Brochard L (2008) Intensive Care Med 34(8):1477–1486
Colombo D, Cammarota G, Bergamaschi V, De Lucia M, Corte FD, Navalesi P (2008) Intensive Care Med 34:2010–2018
Lecomte F, Brander L, Jalde F et al (2009) Respir Physiol Neurobiol 166:117–124
Patroniti N, Bellani G, Saccavino E et al (2012) Intensive Care Med 38:230–239
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Morales Quinteros, L., Ferguson, N.D. (2014). Non-conventional Modes of Ventilation in Patients with ARDS. In: Vincent, JL. (eds) Annual Update in Intensive Care and Emergency Medicine 2014. Annual Update in Intensive Care and Emergency Medicine, vol 2014. Springer, Cham. https://doi.org/10.1007/978-3-319-03746-2_16
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DOI: https://doi.org/10.1007/978-3-319-03746-2_16
Publisher Name: Springer, Cham
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