Abstract
Many cases of depression in women are due to endocrine factors and treatment by antidepressants or mood stabilizing is inappropriate Reproductive Depression includes Premenstrual Depression (PMDD), Postnatal Depression and Climacteric Depression, which is more severe in the transitional phase 2 or 3 years before the periods cease rather than in the years after the menopause. Such patients are usually free of depression during pregnancy. The diagnosis cannot be made by measuring hormone levels but by a careful history relating depression to monthly cycles and the postnatal state. Treatment should be by oestrogens preferably by the transdermal route. The depression is a result of fluctuations of oestradiol and by progestogen intolerance.
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Studd, J., Nappi, R.E. (2014). Reproductive Depression and the Response to Oestrogen Therapy. In: Genazzani, A.R., Brincat, M. (eds) Frontiers in Gynecological Endocrinology. ISGE Series. Springer, Cham. https://doi.org/10.1007/978-3-319-03494-2_23
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DOI: https://doi.org/10.1007/978-3-319-03494-2_23
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