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The Relationship between the 24-h Blood Pressure Variability and Carotid Intima-Media Thickness: A Preliminary Study

  • Dan Wu
  • Huahua Xiong
  • Xiaohong Tian
  • Wan-Hua Lin
  • Chunyue Li
  • Heye Zhang
  • Yuan-Ting Zhang
Part of the IFMBE Proceedings book series (IFMBE, volume 42)

Abstract

Increased blood pressure variability (BPV) will cause the damage of the target-organ and raise the incidence of cardiovascular events. The change of carotid intima-media thickness (CIMT) usually arises from the damage inside the vascular system, and this factor has been used as one early indicator of arteriosclerosis during clinical practice. In this paper we evaluate the relationship between the BPV and the CIMT in 10 randomized patients (aged 62.7±11.4, 50% men). The blood pressure (BP) was collected using the 24-h ambulatory blood pressure monitoring (ABPM), and the BPV measured with standard deviation (SD) were calculated in the daytime, nighttime, and whole day, respectively. All the CIMT measurements were collected using Philips iU22 ultrasound system. The results of this preliminary study showed that the daytime systolic blood pressure variability (SBPV) had a positive correlation with the CIMT (r=0.288), and we haven’t found any relationship between the CIMT, and the diastolic blood pressure variability (DBPV) and 24-h BPV over current samples. However, we found that the correlation of the BPV and CIMT would increase largely if we exclude the patients with diabetes. We expect to carry on a large-scale investigation over Chinese population in the near future.

Keywords

Blood pressure variability Ultrasound Carotid artery Intima-media thickness 

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Copyright information

© Springer International Publishing Switzerland 2014

Authors and Affiliations

  • Dan Wu
    • 1
    • 2
  • Huahua Xiong
    • 3
  • Xiaohong Tian
    • 4
  • Wan-Hua Lin
    • 1
    • 2
  • Chunyue Li
    • 1
    • 2
  • Heye Zhang
    • 1
    • 2
  • Yuan-Ting Zhang
    • 1
    • 2
    • 5
  1. 1.Institute of Biomedical and Health EngineeringShenzhen Institutes of Advanced TechnologyShenzhenChina
  2. 2.Key Lab for Health InformaticsChinese Academy of SciencesShenzhenChina
  3. 3.Department of UltrasoundThe Second Peoples’ Hospital of ShenzhenShenzhenChina
  4. 4.Cardiac Electrocardiogram RoomThe Second Peoples’ Hospital of ShenzhenShenzhenChina
  5. 5.Joint Research Center for Biomedical EngineeringThe Chinese University of Hong KongShatinHong Kong

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