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IMRT Beam Angle Optimization Using Dynamically Dimensioned Search

  • J. Dias
  • H. Rocha
  • B. Ferreira
  • M. C. Lopes
Part of the IFMBE Proceedings book series (IFMBE, volume 42)

Abstract

In Intensity Modulated Radiation Therapy (IMRT), the selection of appropriate radiation incidence directions is one of the determinants of proper tumor coverage and sparing of healthy tissues. Nevertheless, most of the times, the incidence directions used in clinical practice are equidistant or determined by a trial and error procedure that is very time consuming and does not guarantee the best possible treatment plan. This paper presents some preliminary results considering the application of DDS (Dynamically Dimensioned Search) algorithm to the problem of Beam Angle Optimization (BAO) for IMRT treatment planning. BAO is a problem known by having many local minima. DDS is a derivative-free optimization algorithm, and presents the capability of not getting trapped in these local minima as happens with, for instance, gradient descent based algorithms. In this paper we will briefly describe the problem, the algorithm, and present computational results for clinical cases of head and neck tumors.

Keywords

Radiotherapy IMRT Beam Angle Optimization DDS 

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Copyright information

© Springer International Publishing Switzerland 2014

Authors and Affiliations

  • J. Dias
    • 1
  • H. Rocha
    • 2
  • B. Ferreira
    • 3
    • 4
  • M. C. Lopes
    • 3
    • 4
  1. 1.Faculty of Economics and Inesc-CoimbraUniversity of CoimbraCoimbraPortugal
  2. 2.Inesc-CoimbraCoimbraPortugal
  3. 3.IPOC-FG, EPECoimbraPortugal
  4. 4.I3N, Campus Universitário de SantiagoAveiroPortugal

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