Abstract
The rate of severe ear malformations (n=259) were non-significantly increased at high maternal age and significantly increased at first parity, if the mother smoked, or if she was overweight or obese. No significant association with maternal drug use was seen.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Canfield MA, Langlois PH, Nouyen LM, Scheuerie AE. Epidemiologic features and clinical subgroups of anotia/microtia in Texas. Birth Def Res A. 2009;85:905–13.
Forrester MB, Merz RD. Descriptive epidemiology of anotia and microtia, Hawaii, 1986–2002. Congenit Anom. 2005;45:119–24.
Harris J, Källén B, Robert E. The epidemiology of anotia and microtia. J Med Genet. 1996;33:809–13.
Lee KT, Yang E-J, Lim S-Y, Pyon J-K, Mun G-H, Bang S-I, Oh KS. Association of congenital microtia with environmental risk factors in South Korea. Int J Pediatr Otorhinolaryngol. 2012;76:357–61.
Lisi A, Botto LD, Rittler M, Castilla E, Bianchi F, Botting B, De Walle H, Erickson JD, Gatt M, De Vigan C, Irgens L, Johnson W, Lancaster P, Merlob P, Mutchinick OM, Ritvanen A, Robert E, Scarano G, Stoll C, Mastroiacovo P. Sex and congenital malformations: an international perspective. Am J Med Genet. 2005;134A:49–57.
Luquetti DV, Leoncini E, Mastroiacovo P. Microtia-anotia: a global review of prevalence rates. Birth Def Res A. 2011;91:813–22.
Mastroiacovo P, Corchia C, Botto LD, Lanni R, Zampino G, Fusco D. Epidemiology and genetics of microtia-anotia: a registry based study on over one million births. J Med Genet. 1995;32:453–7.
Paput L, Bánhidy F, Czeizel AE. Maternal characteristics and birth outcomes of pregnant women who had offspring with congenital ear abnormalities – a population-based case–control study. J Matern Fetal Neonatal Med. 2011a;24:1107–14.
Paput L, Czeizel AE, Bánhidy E. Maternal diseases and risk of isolated ear abnormalities in their children. Cent Eur J Public Health. 2011b;19:170–6.
Paput L, Bánhidy E, Czeizel AE. Association of drug treatments in pregnant women with the risk of external ear congenital abnormalities in their offspring: a population-based case–control study. Congenit Anom. 2011c;51:126–37.
Shaw GM, Carmichael SL, Maidarova Z, Harris JA. Epidemiologic characteristics of anotia and microtia in California, 1989–1997. Birth Defects Res A. 2004;70:472–5.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2014 Springer International Publishing Switzerland
About this chapter
Cite this chapter
Källén, B. (2014). Severe Ear Malformations. In: Epidemiology of Human Congenital Malformations. Springer, Cham. https://doi.org/10.1007/978-3-319-01472-2_11
Download citation
DOI: https://doi.org/10.1007/978-3-319-01472-2_11
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-01471-5
Online ISBN: 978-3-319-01472-2
eBook Packages: MedicineMedicine (R0)