Infrared Photodissociation of Biomolecular Ions
The emphasis of this chapter is on applications of vibrational spectroscopy to derive structural information of biomolecular ions. The section is organized by spectroscopic techniques and the types of tunable light sources that are employed. The potentials and limitations of these approaches with respect to recording infrared spectra are discussed, as well as the types of molecular systems that they can be applied to. The primary benefit of measuring infrared spectra on biomolecular ions derives from the compositional and structural information based on diagnostic vibrations. It is shown that IR spectroscopy in many cases is capable of distinguishing isomers. Moreover, cold spectroscopy methods provide extremely detailed structural information on gas-phase conformations. This chapter closes on an outlook of expected applications of infrared spectroscopy of biomolecules, focusing on the example of metabolites.
KeywordsCrown Ether Mass Channel chEMBL Database Photodissociation Spectrum Tunable Light Source
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