Protein Folding: An Introduction

  • Cláudio M. GomesEmail author
  • Patrícia F. N. FaíscaEmail author
Part of the SpringerBriefs in Molecular Science book series (BRIEFSMOLECULAR)


We have come a long way since coining of the term protein and the early findings that proteins are charged macromolecules composed of strings of amino acids linked by peptide bonds. Today, structural biologists have technologies that allow in many cases to achieve an atomic-level understanding of protein structure, dynamics and folding; protein physics approaches have made substantial contributions to understanding the intricacies of folding mechanisms and its energetics; biochemists have developed conceptual frameworks to relate protein structure with biological functions. Yet, despite the efforts of a vibrant community of protein scientists, a lot of questions remain to be answered in the field of protein structure and folding.


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Copyright information

© The Author(s), under exclusive license to Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Chemistry and Biochemistry, Faculty of SciencesBiosystems & Integrative Sciences Institute, University of LisbonLisbonPortugal
  2. 2.Department of Physics, Faculty of SciencesBiosystems & Integrative Sciences Institute, University of LisbonLisbonPortugal

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