Boolean Model of the Cell Cycle Response to Stress

Chapter
Part of the Springer Theses book series (Springer Theses)

Abstract

Understanding complex biological systems, e.g. the cell cycle, requires not only sophisticated experimental techniques but also adequate mathematical models. Many different mathematical approaches, from quantitive to qualitative, from continuous to discrete, have been applied to study the cell in different environmental conditions. In this chapter, we introduce a second complementary modelling approach to study the response of the cell cycle to osmotic and alpha-factor signal: we construct a Boolean network which describes the dynamical behaviour of the cell cycle response to multiple extracellular signals.

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Copyright information

© Springer International Publishing Switzerland 2014

Authors and Affiliations

  1. 1.Department of Physics, Institute of Complex Systems and Mathematical BiologyUniversity of AberdeenOld AberdeenUK

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