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Basement Membrane

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Functional Ultrastructure

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Abstract

Basement membranes are thin sheets of specialised extracellular matrix, supporting epithelial cell layers and covering muscle cells and nerve fibres. Basement membranes not only provide a particular support for tissues, but also have essential roles in cell differentiation and movement, in morphogenesis and new formation of organs and in multiple pathological processes, such as tumour growth and migration. Basement membranes consist of two different layers (laminae), which can easily be distinguished under the electron microscope: the basal lamina (Lb, lamina basalis) and the reticular lamina (Lf, lamina fibroreticularis).

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References

  • Brown E and Dejana E (2003) Cell-to-cell contact and extracellular matrix. Editorial overview: Cell-cell and cell-matrix interactions — running, jumping, standing still. Curr Opin Cell Biol 15: 505

    Article  CAS  Google Scholar 

  • Danen EHJ and Sonnenberg A (2003) Integrins in regulation of tissue development and function. J Pathol 200: 471

    Article  CAS  PubMed  Google Scholar 

  • Sakai T, Larsen M, and Yamada KM (2003) Fibronectin requirement in branching morphogenesis. Nature 423: 876

    Article  CAS  PubMed  Google Scholar 

  • Schwarzbauer JE and Sechler JL (1999) Fibronectin fibrillogenesis: a paradigm for extracellular matrix assembly. Curr Opin Cell Biol 11: 622

    Article  CAS  PubMed  Google Scholar 

  • Timpl R, Sasaki T, Kostka G, and Chu M-L (2003) Fibulins: A versatile family of extracellular matrix proteins. Nat Rev Mol Cell Biol 4: 479

    Article  CAS  PubMed  Google Scholar 

  • White JM (2003) ADAMs: modulators of cell-cell and cell-matrix interaction. Curr Opin Cell Biol 15: 598

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Center for Anatomy and Cell Biology, Department of Cell Biology and Ultrastructure Research, Medical University of Vienna, Vienna, Austria

    o. Univ. Prof. Dr. med. Margit Pavelka

  2. Yonsei University Graduate School, World Class University Program, Department of Biomedical Science, Yonsei University, Seoul, Korea

    Prof. Dr. med. Dr. sc. Dr. h. c. Jürgen Roth

Authors
  1. o. Univ. Prof. Dr. med. Margit Pavelka
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  2. Prof. Dr. med. Dr. sc. Dr. h. c. Jürgen Roth
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© 2010 Springer-Verlag/Wien

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Pavelka, M., Roth, J. (2010). Basement Membrane. In: Functional Ultrastructure. Springer, Vienna. https://doi.org/10.1007/978-3-211-99390-3_94

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