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Selectin — Ligand-Mediated Cell-Cell Interaction

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Functional Ultrastructure
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Abstract

Neutrophilic leukocytes and naïve lymphocytes may interact in a specific manner with the endothelial cells lining the capillaries in various organs. This occurs during physiological recirculation (or homing) of lymphoid cells and diapedesis (extravasation) of leukocytes, and during infection or injury as well as inflammation by interaction of these cells with the activated endothelium. For this cell-cell interaction to occur, selectins and cell-surface glycans (as ligands) are important.

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Pavelka, M., Roth, J. (2010). Selectin — Ligand-Mediated Cell-Cell Interaction. In: Functional Ultrastructure. Springer, Vienna. https://doi.org/10.1007/978-3-211-99390-3_91

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