Abstract
Membranoproliferative glomerulonephritis is representative of different disease entities with different aetiologies and clinical signs. The type-1 membranoproliferative glomerulonephritis is an immune complex-mediated disease that can be classified in primary (idiopathic) forms caused by unknown antigens and secondary forms. The latter are associated with different diseases such as infections, tumours, and systemic immune abnormalities. Among the infectious diseases, hepatitis C is the predominant cause. The causative factors of the membranoproliferative glomerulonephritis are circulating immune complexes, and this results in the secondary activation of the classical complement pathway.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Burstein DM and Rodby RA (1993) Membranoproliferative glomerulonephritis associated with hepatitis C virus infection. J Am Soc Nephrol 4: 1288
Cohen A and Nast C (1996) Kidney. In: Anderson’s pathology. (Damjanov I and Linder J, eds). St. Louis: Mosby, pp 2073
Dickersin G (2000) Diagnostic electron microscopy. A text/atlas. New York: Springer
West CD (1992) Idiopathic membranoproliferative glomerulonephritis in childhood. Pediatr Nephrol 6: 96
Zollinger H and Mihatsch M (1978) Renal pathology in biopsy. Berlin Heidelberg New York: Springer
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2010 Springer-Verlag/Wien
About this chapter
Cite this chapter
Pavelka, M., Roth, J. (2010). Pathology of the Glomerulus: Membranoproliferative Glomerulonephritis. In: Functional Ultrastructure. Springer, Vienna. https://doi.org/10.1007/978-3-211-99390-3_138
Download citation
DOI: https://doi.org/10.1007/978-3-211-99390-3_138
Publisher Name: Springer, Vienna
Print ISBN: 978-3-211-99389-7
Online ISBN: 978-3-211-99390-3
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)