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Analysis of Free Radicals in Biological Systems pp 119–126Cite as

EPR evidence of generation of superoxide anion radicals (O ·-2 ) by irradiation of a PDT photosensitizer: Hypericin

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Summary

Irradiation of hypericin in EYL liposomes with visible light under aerobic conditions at pH 7, produced superoxide anion radicals which were detected with the spin trap 5,5-dimethyl-1-pyrroline-1-oxide(D MPO).

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Author information

Authors and Affiliations

  1. Laboratoire de Photochimie, Université Joseph Fourier, BP 53, F-38041, Grenoble Cédex 9, France

    C. Hadjur

  2. LEDSS, Université Joseph Fourier, BP 53, F-38041, Grenoble Cédex 9, France

    A. Jeunet

Authors
  1. C. Hadjur
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  2. A. Jeunet
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Editor information

Editors and Affiliations

  1. Laboratoire de Biochimie C, CHU Albert Michallon, BP 217, F-38043, Grenoble Cédex 9, France

    A. E. Favier

  2. CEA/Département de Recherche Fondamentale sur la Matière, Condensée, SESAM/LAN, 17, rue des Martyrs, F-38054, Grenoble Cédex 9, France

    J. Cadet

  3. Biophysics Research Institute, Medical College of Wisconsin, 8701 Watertown Plank Road, PO Box 26509, Milwaukee, WI, 53226-0509, USA

    B. Kalyanaraman

  4. Laboratoire de Biochimie Recherche, Domaine Universitaire, F-38400, Saint Martin d’Hères, France

    M. Fontecave

  5. Laboratoire de Chimie Biomimétique LEDSS II, Domaine Universitaire, F-38400, Saint Martin d’Hères, France

    J.-L. Pierre

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© 1995 Birkhäuser Verlag Basel/Switzerland

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Hadjur, C., Jeunet, A. (1995). EPR evidence of generation of superoxide anion radicals (O ·-2 ) by irradiation of a PDT photosensitizer: Hypericin. In: Favier, A.E., Cadet, J., Kalyanaraman, B., Fontecave, M., Pierre, JL. (eds) Analysis of Free Radicals in Biological Systems. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-9074-8_9

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  • DOI: https://doi.org/10.1007/978-3-0348-9074-8_9

  • Publisher Name: Birkhäuser Basel

  • Print ISBN: 978-3-0348-9895-9

  • Online ISBN: 978-3-0348-9074-8

  • eBook Packages: Springer Book Archive

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