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Angiogenesis as a component of epithelial-mesenchymal interactions

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Book cover Epithelial-Mesenchymal Interactions in Cancer

Part of the book series: Experientia Supplementum ((EXS,volume 74))

Summary

Here we review the role of angiogenesis as it pertains to the interactions between the epithelium and the mesenchyme, especially during tumor growth and metastasis. We illustrate and discuss several models of angiogenesis including endothelial tube formation on Matrigel. Finally, we examine angiogenic factors using the Matrigel model and investigate several other matrix molecules for their importance in angiogenesis and epithelial/stromal interactions.

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Author information

Authors and Affiliations

  1. Cardeza Foundation for Hematological Research, Thomas Jefferson University, College of Medicine, 1015 Walnut St., Curtis 703, Philadelphia, PA, 19107, USA

    D. S. Grant & R. Wesley Rose

  2. Gerontology Research Center, National Institute on Aging, NIH, Baltimore, MD, 21224, USA

    M. C. Kibbey

  3. Laboratory of Development Biology, National Institute of Dental Research, NIH, Bethesda, MD, 20892, USA

    J. K. Kinsella

Authors
  1. D. S. Grant
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  2. R. Wesley Rose
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  3. J. K. Kinsella
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  4. M. C. Kibbey
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Editor information

Editors and Affiliations

  1. Institute of Oncology, Long Island Jewish Medical Center, New Hyde Park, N.Y., 11042, USA

    I. D. Goldberg  & E. M. Rosen  & 

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© 1995 Birkhäuser Verlag

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Grant, D.S., Rose, R.W., Kinsella, J.K., Kibbey, M.C. (1995). Angiogenesis as a component of epithelial-mesenchymal interactions. In: Goldberg, I.D., Rosen, E.M. (eds) Epithelial-Mesenchymal Interactions in Cancer. Experientia Supplementum, vol 74. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-9070-0_12

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  • DOI: https://doi.org/10.1007/978-3-0348-9070-0_12

  • Publisher Name: Birkhäuser Basel

  • Print ISBN: 978-3-0348-9893-5

  • Online ISBN: 978-3-0348-9070-0

  • eBook Packages: Springer Book Archive

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