Summary
The pancreatic endocrine cells reveal their paraneuronal nature by forming, with intrapancreatic neurons, a neuro-insular complex. Studies on this peculiar structure opened up a new field of neurosecretion in the pancreas. Recent studies on enterochromaffin cells, which constitute one of the most typical categories of paraneurons in the gut, are reviewed with special reference to their involvement in the pathogenesis of diarrhea and to the possibility of their partially exocrine activity. This review further deals with “Segi’s cap”, an endocrine cell aggregation at the villus tip in the small intestine in the human and bovine fetus. Recent studies suggest that the paraneurons forming Segi’s cap migrate, during the perinatal period, into the interstitium, where they develop more neuronal features and are incorporated in the intramural nerve plexus.
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© 1996 Birkhäuser Verlag Basel/Switzerland
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Fujita, T. (1996). The paraneuron revisited. In: Krisch, B., Mentlein, R. (eds) The Peptidergic Neuron. Advances in Life Sciences. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-9010-6_3
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DOI: https://doi.org/10.1007/978-3-0348-9010-6_3
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