Skip to main content

Non-opioid analgesics in cancer pain relief

  • Conference paper
Non-Opioids in Pain Management
  • 60 Accesses

Abstract

Morphine and other strong opioids are the mainstay of cancer pain treatment. The development of new drug formulations and sophisticated delivery systems has further increased the flexibility of opioid therapy. What place, then, do non-opioids have in the management of cancer pain?

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Schug, S.A., Zech, D., Doerr, U., Cancer pain management according to WHO Analgesic Guidelines in the course of time. J. Pain Symptom Manage. 5, 27–32 (1990).

    Article  PubMed  CAS  Google Scholar 

  2. Schug, S.A., Zech, D., Grond, S., et al, A long-term survey of morphine in cancer pain patients. J. Pain Symptom Manage. 7, 259–266 (1992).

    Article  PubMed  CAS  Google Scholar 

  3. Drage, M.P., Schug, S.A., Analgesia in the elderly — Practical treatment recommendations. Drugs Aging 9, 311–318 (1996).

    Article  PubMed  CAS  Google Scholar 

  4. Schug, S.A., Payne, J.P., Dijkhuizen, M.R.J., Routine analgesia after day stay surgery: slow release dihydrocodeine compared with paracetamol. Abstracts 8th World Congress of Pain, IASP Press, Seattle 267 (1996).

    Google Scholar 

  5. Cooper, S.A., Comparative analgesic efficacies of aspirin and acetaminophen. Arch. Intern. Med. 141, 282–285 (1981).

    Article  PubMed  CAS  Google Scholar 

  6. Sidebotham, D.A., Schug, S.A., McGuinnety, M., Fox, L., The addition of acetaminophen to patient controlled analgesia in the management of acute postoperative pain. Abstract submitted for presentation at 22nd Annual Meeting of ASRA, Atlanta (1997).

    Google Scholar 

  7. Zimmerman, H.J., Maddrey, W.C., Acetaminophen hepatotoxicity with regular intake of alcohol: analysis of instances of therapeutic misadventure. Hepatology 22, 767–773 (1995).

    Article  PubMed  CAS  Google Scholar 

  8. Seyberth, H.W., Prostaglandin-mediated hypercalcemia: a paraneoplastic syndrome. Klin. Wschr. 56, 373–387 (1978).

    Article  PubMed  CAS  Google Scholar 

  9. Eisenberg, E., Berkey, C.S., Carr, D.B., Mosteller, E, Chalmers, T.C., Efficacy and safety of nonsteroidal antiinflammatory drugs for cancer pain: a meta-analysis. J. Clin. Oncol. 12, 2756–2765 (1994).

    PubMed  CAS  Google Scholar 

  10. Stambaugh, J.E., Drew, J., The combination of ibuprofen and oxycodone/ acetaminophen in the treatment of chronic cancer pain. Clin. Pharmacol. Ther. 44, 665–669 (1988).

    Article  PubMed  Google Scholar 

  11. Ferrer-Brechner, T., Ganz, P., Combination therapy with ibuprofen and methadone for chronic cancer pain. Am. J. Med. 77, 78–83 (1984).

    Article  PubMed  CAS  Google Scholar 

  12. Kaufman, D.W., Kelly, J.P., Sheehan, J.E., et al., Nonsteroidal anti-inflammatory drug use in relation to major upper gastrointestinal bleeding. Clin. Pharmacol. Ther. 53, 485–494 (1993).

    Article  PubMed  CAS  Google Scholar 

  13. García Rodríguez, L.A., Jick, H., Risk of upper gastrointestinal bleeding and perforation associated with individual non-steroidal anti-inflammatory drugs. Lancet 343, 769–772 (1994).

    Article  Google Scholar 

  14. Langman, M.J.S., Weil, J., Wainwright, P., et al., Risks of bleeding peptic ulcer associated with individual non-steroidal anti-inflammatory drugs. Lancet 343, 1075–1078 (1994).

    Article  PubMed  CAS  Google Scholar 

  15. Gomez-Jiminez, J., Franco-Patino, R., Chargoy-Vera, J., Olivares-Sosa, R., Clinical efficacy of mild analgesics in pain following gynaecological or dental surgery. Br. J. Clin. Pharmac. 10, 355S–358S (1980).

    Article  Google Scholar 

  16. Patel, C.V., Koppikar, M.G., Patel, M.S., Parulkar, G.B., Pinto-Pereira, L.M., Management of pain after abdominal surgery: dipyrone compared with pethidine. Br. J. Clin. Pharmacol. 10, 351S–354S (1980).

    Article  PubMed  Google Scholar 

  17. Miralies, R., Cami, J., Gutierrez, J., et al, Diclofenac versus dipyrone in acute renal colic; a double-blind controlled trial. Eur. J. Clin. Pharm. 33, 527–528 (1987).

    Article  Google Scholar 

  18. Rodríguez, M., Barutell, C., Rull, M., et al., Efficacy and tolerance of oral dipyrone versus oral morphine for cancer pain. Eur. J. Cancer 30A, 584–587 (1994).

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1997 Springer Basel AG

About this paper

Cite this paper

Schug, S.A. (1997). Non-opioid analgesics in cancer pain relief. In: Parnham, M.J. (eds) Non-Opioids in Pain Management. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-8904-9_5

Download citation

  • DOI: https://doi.org/10.1007/978-3-0348-8904-9_5

  • Publisher Name: Birkhäuser, Basel

  • Print ISBN: 978-3-7643-5700-9

  • Online ISBN: 978-3-0348-8904-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics