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Computer modeling of protein, nucleic acid, and drug structures

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Microsystem Technology

Part of the book series: BioMethods ((BIOMETHODS))

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Abstract

Microsystem technology is devoted to the handling of small amounts of chemicals and biochemicals. It can assist and is in fact a necessary requirement for all types of automatic processes including optimization. In addition to the technological aspects a basic understanding of the molecular structures to be processed is a sine qua non for the successful automatization in general and for the optimization of desired functions in particular. Computer modeling of biopolymer and drug structures has already proven to be helpful and becomes even more important if large numbers of structures are to be processed. Molecular modeling can also contribute to the design of nanostructures (Russell et al., 1997; Stupp et al., 1997). This aspect is beyond the scope of this contribution, however. Therefore, this chapter is focused on the application of computational and theoretical approaches to the structure modeling of proteins, nucleic acids, and drugs. It covers a relatively broad subject and cannot be very specific or comprehensive. Rather, it is intended as an introductory reading to modeling techniques and their application. More in-depth information should easily be possible both via the references and the sampling of web resources.

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Authors
  1. Jürgen Sühnel
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Editors and Affiliations

  1. Institut für Physikal, Hochtechnologie Jena, Hemholtzweg 4, D-07743, Jena, Germany

    J. M. Köhler

  2. Rosenstr. 7, D-07749, Jena, Germany

    T. Mejevaia

  3. Hans-Knöll-Institut für Naturstofforschung e.V., Beutenbergstr. 11, D-07745, Jena, Germany

    H. P. Saluz

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Sühnel, J. (1999). Computer modeling of protein, nucleic acid, and drug structures. In: Köhler, J.M., Mejevaia, T., Saluz, H.P. (eds) Microsystem Technology. BioMethods. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-8817-2_20

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  • DOI: https://doi.org/10.1007/978-3-0348-8817-2_20

  • Publisher Name: Birkhäuser, Basel

  • Print ISBN: 978-3-0348-9784-6

  • Online ISBN: 978-3-0348-8817-2

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