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Prognostic Potential of Tc-99m-ECD-SPET Within 6 Hours after Onset of Stroke Symptoms

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Radioactive Isotopes in Clinical Medicine and Research XXIII

Abstract

The aim of this present study was to evaluate the prognostic impact of early SPET after stroke. 108 patients underwent SPET (400 — 600 MBq Tc-99m-ECD, brain dedicated camera) within 6h after onset of stroke symptoms. In follow-up period CT revealed no hypodensities (n = 20), subtotal medial cerebri artery territory (MCA) hypodensities (n = 78) or total MCA territory hypodensities (n = 10). Sensitivity and specificity of visual SPET analysis equaled 96.1% and 90.0%. Semiquantitative SPET analysis revealed significant group differences regarding size and depth of early activity deficits. Using cut-off values for these parameters, clinical outcome after 5d was correctly predicted in 89/108 patients.

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© 1999 Springer Basel AG

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Barthel, H. et al. (1999). Prognostic Potential of Tc-99m-ECD-SPET Within 6 Hours after Onset of Stroke Symptoms. In: Bergmann, H., Köhn, H., Sinzinger, H. (eds) Radioactive Isotopes in Clinical Medicine and Research XXIII. Advances in Pharmacological Sciences. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-8782-3_5

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  • DOI: https://doi.org/10.1007/978-3-0348-8782-3_5

  • Publisher Name: Birkhäuser, Basel

  • Print ISBN: 978-3-0348-9772-3

  • Online ISBN: 978-3-0348-8782-3

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