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Assessment of Pulmonary Nodules and Colorectal Cancer Recurrences by FDG Scan on an «Ordinary» Coincidence Gamma Camera (CDET)

  • D. Grahek
  • F. Montravers
  • N. Ghazzar
  • S. Ait Ben Ali
  • N. Younsi
  • K. Kerrou
  • M. Wartski
  • E. Zerbib
  • J. Lumbroso
  • J. N. Talbot
Part of the Advances in Pharmacological Sciences book series (APS)

Abstract

A FDG-CDET examination on a Picker gamma-camera equiped with coincidence detection and thick cristals was performed in 80 patients during the 2nd half of 1997. Sensitivity and specificity were both 100% for the detection of malignancy in primary lung tumours. Accuracy was 91% for the detection of hilar or mediastinal lymph nodes involvement vs 59% for CT; lymphangitic carcinomatosis, metastases and concomittant tumours were also successfully detected and confirmed. FDG-CDET contributed to significant management changes in 30% of the patients referred for lung abnormalities. FDG-CDET was also usefull in “occult” recurrence of colorectal cancer with an accuracy of 78% vs 42% for CT in this difficult indication; a longer follow-up is needed to be able to evaluate all the 25 patients whose management have been adequately modified in 60% of the cases. We conclude that the diagnostic performances of FDG-CDET derived from our current series cannot be distinguished from the corresponding results published with FDG-PET.

Keywords

Positron Emission Tomography Pulmonary Nodule Positron Emission Tomography Scanner Coincidence Detection Dual Head Gamma Camera 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Hustinx R, Paulus P, Rigo P, Yeung HW, Macxapinlac HA, Larson SM. In: Clinical PET in oncology. Lung tumors. GE Medical Systems Editor; 1996: 16–31.Google Scholar
  2. 2.
    Dewan NA, Reeb SD, Gupta NC et al. PET-FDG imaging and transthoracic needle lung aspiration biopsy in evaluation of pulmonary lesions. A comparative risk-benefit analysis. Chest 1995; 108: 441–446.PubMedCrossRefGoogle Scholar
  3. 3.
    Valk PE, Pounds TR, Hopkins DM et al. Staging non-small cell lung cancer by whole body positron emission tomographic imaging. Ann Thorac. Surg. 1995; 60: 1573–82.PubMedCrossRefGoogle Scholar
  4. 4.
    Wahl RL, Quint LE, Greenough RL et al. Staging of mediastinal non-small cell lung cancer with FDG PET, CT and fusion images: preliminary prospective evaluation. Radiology 1994; 191: 371–377.PubMedGoogle Scholar
  5. 5.
    Inoue T, Kim EE, Komki R et al. Detecting recurrent or residual lung cancer with FDG-PET. J Nucl Med 1995; 36: 788–793PubMedGoogle Scholar
  6. 6.
    Lewis P, Griffin S, Marsden P et al. Whole body 18F-fluorodeoxyglucose positron emission tomography in preoperative evaluation of lung cancer. Lancet 1994; 344: 1265–1266.PubMedCrossRefGoogle Scholar
  7. 7.
    Hustinx R, Paulus P, Rigo P, Yeung HW, Macxapinlac HA, Larson SM. In: Clinical PET in oncology. Tumors of the gastro-intestinal tract. GE Medical Systems Editor; 1996: 32–45.Google Scholar
  8. 8.
    Schiepers C, Penninckx F, De Vadder N et al. Contribution of PET in the diagnosis of recurrent colorectal cancer. Eur J Surg Oncol 1995; 21: 517–522.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Basel AG 1999

Authors and Affiliations

  • D. Grahek
    • 1
  • F. Montravers
    • 1
  • N. Ghazzar
    • 1
  • S. Ait Ben Ali
    • 1
  • N. Younsi
    • 1
  • K. Kerrou
    • 1
  • M. Wartski
    • 2
  • E. Zerbib
    • 2
  • J. Lumbroso
    • 3
  • J. N. Talbot
    • 1
  1. 1.Services de médecine nucléaireHôpital TenonParisFrance
  2. 2.Services de médecine nucléaireCentre Chirurgical Marie LannelongueLe Plessis RobinsonFrance
  3. 3.Services de médecine nucléaireInstitut Gustave RoussyVillejuifFrance

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