Abstract
A prospective trial was started to evaluate the efficacy of 99m-Tc-tetrofosmin scintigraphy for monitoring the clinical course of thirty-one patients getting neoadjuvant chemotherapy suffering from breast cancer. Clinical and imaging procedures were done at the beginning of treatment and just before surgery. Sensitivity for breast cancer was 69% for mammography, 85% for ultrasound and 96% for 99m-Tc-tetrofosmin scintigraphy. We discovered two cases of bone and two cases of lung metastases by means of 99m-Tc-tetrofosmin scintigraphy. Eight of ten detected suspicious thoracic areas were not confirmed by CT or clinical course.
These findings show that 99m-Tc-tetrofosmin scintigraphy is the most sensitive imaging technique to detect breast cancer. Preliminary data indicate that it might be also become the method of choice for monitoring treatment efficacy.
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© 1999 Springer Basel AG
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Obwegeser, R., Müllauer-Ertl, S., Berghammer, P., Kubista, E., Sinzinger, H. (1999). Neoadjuvant Treatment of Patients with Breast Cancer under Surveillance of 99m-Tc-Tetrofosmin Scintigraphy. In: Bergmann, H., Köhn, H., Sinzinger, H. (eds) Radioactive Isotopes in Clinical Medicine and Research XXIII. Advances in Pharmacological Sciences. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-8782-3_25
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DOI: https://doi.org/10.1007/978-3-0348-8782-3_25
Publisher Name: Birkhäuser, Basel
Print ISBN: 978-3-0348-9772-3
Online ISBN: 978-3-0348-8782-3
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