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Advanced Stage Thyroid Cancer — Treatment with Isotretinoin

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Book cover Radioactive Isotopes in Clinical Medicine and Research XXIII

Part of the book series: Advances in Pharmacological Sciences ((APS))

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Abstract

Isotretinoin has been successfully applied in a variety of malignant tumours displaying growth inhibiting and differentiation enhancing effects. As cell culture studies have proposed positive responses to Isotretinoin in differentiated thyroid cancer we applied the vitamin A derivative to 15 patients with advanced metastatic thyroid cancer. 14 patients showed at least a partial response in Tg, FDG PET or radioiodine measurements. In conclusion, Isotretinoin is useful in advanced thyroid cancer.

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Author information

Authors and Affiliations

  1. Inst. of Medicine Research Centre Jülich Dept. of Nuclear Medicine, University Düsseldorf, Germany

    A. R. Börner, D. Simon, M. Weckesser, K.-J. Langen, H.-D. Röher & H.-W. Müller-Gärtner

  2. Inst. of Medicine Research Centre Jülich Dept. of General and Trauma Surgery, University Düsseldorf, Germany

    A. R. Börner, D. Simon, M. Weckesser, K.-J. Langen, H.-D. Röher & H.-W. Müller-Gärtner

Authors
  1. A. R. Börner
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  2. D. Simon
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  3. M. Weckesser
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  4. K.-J. Langen
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  5. H.-D. Röher
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  6. H.-W. Müller-Gärtner
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Editor information

Editors and Affiliations

  1. Institut für Biomedizinische Technik und Physik, Allgemeines Krankenhaus Wien, Währinger Gürtel 18-20, A-1090, Wien, Austria

    Helmar Bergmann

  2. Institut für Nuklearmedizin, Wilhelminenspital, Montleartstrasse 37, A-1171, Wien, Austria

    Horst Köhn

  3. Universitäts-Klinik für Nuklearmedizin, Allgemeines Krankenhaus Wien, Währinger Gürtel 18-20, A-1090, Wien, Austria

    Helmut Sinzinger

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© 1999 Springer Basel AG

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Börner, A.R., Simon, D., Weckesser, M., Langen, KJ., Röher, HD., Müller-Gärtner, HW. (1999). Advanced Stage Thyroid Cancer — Treatment with Isotretinoin. In: Bergmann, H., Köhn, H., Sinzinger, H. (eds) Radioactive Isotopes in Clinical Medicine and Research XXIII. Advances in Pharmacological Sciences. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-8782-3_20

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  • DOI: https://doi.org/10.1007/978-3-0348-8782-3_20

  • Publisher Name: Birkhäuser, Basel

  • Print ISBN: 978-3-0348-9772-3

  • Online ISBN: 978-3-0348-8782-3

  • eBook Packages: Springer Book Archive

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