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Keratinocytes as a cellular source of inflammatory eicosanoids

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Book cover Fatty Acids and Inflammatory Skin Diseases

Part of the book series: Progress in Inflammation Research ((PIR))

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Abstract

The term ‘eicosanoid’ was introduced by Corey et al. [1] and comprises a large and complex family of compounds derived from 20-carbon polyunsaturated fatty acids, among which arachidonic acid is the most biologically relevant. This group of substances includes prostaglandins, thromboxanes, leukotrienes, hydroperoxy- and hydroxyeicosatetraenoic acids (HPETEs and HETEs), hepoxilins, lipoxins, triox-ilins, nonleukotriene dihydroxyeicosatetraenoic acids (DiHETEs) and isoprostanes.

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  1. Laboratory of Inflammation Mediators, Institute of Research of the Santa Creu and Sant Pau Hospital, S. Antonio Ma Claret 167, E-08025, Barcelona, Spain

    Luis Vila, Rosa Antón & Mercedes Camacho

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  1. Luis Vila
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  2. Rosa Antón
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  3. Mercedes Camacho
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  1. Department of Dermatology, University of Kiel, Schittenhelmstr. 7, D-24105, Kiel, Germany

    Jens-Michael Schröder

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Vila, L., Antón, R., Camacho, M. (1999). Keratinocytes as a cellular source of inflammatory eicosanoids. In: Schröder, JM. (eds) Fatty Acids and Inflammatory Skin Diseases. Progress in Inflammation Research. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-8761-8_7

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  • DOI: https://doi.org/10.1007/978-3-0348-8761-8_7

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