• Li Cher Loh
  • Neil C. Barnes
Part of the Progress in Inflammation Research book series (PIR)


Airway inflammation is fundamental to the disease process in chronic asthma. Different components of the immune system play important roles in perpetuating and orchestrating this inflammatory response. Many types of cells are involved, the airway epithelium is shed; eosinophils, T lymphocytes, polymorphonuclear cells, mast cells, and macrophages are present in an activated state and release proinflammatory mediators, cytokines and growth factors. From inflammation, a process of healing and repair may follow and this has been postulated to lead to remodeling of the airways.


Mast Cell Airway Inflammation Severe Asthma Immunosuppressive Agent Allergy Clin Immunol 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Basel AG 1999

Authors and Affiliations

  • Li Cher Loh
    • 1
  • Neil C. Barnes
    • 1
  1. 1.Department of Respiratory MedicineThe London Chest HospitalLondonUK

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