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Immunomodulators

  • Chapter
Anti-Inflammatory Drugs in Asthma

Part of the book series: Progress in Inflammation Research ((PIR))

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Abstract

Airway inflammation is fundamental to the disease process in chronic asthma. Different components of the immune system play important roles in perpetuating and orchestrating this inflammatory response. Many types of cells are involved, the airway epithelium is shed; eosinophils, T lymphocytes, polymorphonuclear cells, mast cells, and macrophages are present in an activated state and release proinflammatory mediators, cytokines and growth factors. From inflammation, a process of healing and repair may follow and this has been postulated to lead to remodeling of the airways.

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Author information

Authors and Affiliations

  1. Department of Respiratory Medicine, The London Chest Hospital, Bonner Rd, London, E2 9JX, UK

    Li Cher Loh & Neil C. Barnes

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  1. Li Cher Loh
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  2. Neil C. Barnes
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Editors and Affiliations

  1. Immunopharmacology Group, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, UK

    Anthony P. Sampson  & Martin K. Church  & 

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© 1999 Springer Basel AG

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Loh, L.C., Barnes, N.C. (1999). Immunomodulators. In: Sampson, A.P., Church, M.K. (eds) Anti-Inflammatory Drugs in Asthma. Progress in Inflammation Research. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-8751-9_7

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  • DOI: https://doi.org/10.1007/978-3-0348-8751-9_7

  • Publisher Name: Birkhäuser, Basel

  • Print ISBN: 978-3-0348-9757-0

  • Online ISBN: 978-3-0348-8751-9

  • eBook Packages: Springer Book Archive

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