Abstract
Collectively, over 35 million Americans suffer from the various arthritidies with an annual cost estimated to be greater than 18 billion dollars annually [1]. Rheumatoid arthritis (RA) is a progressive, autoimmune disease that primarily affects diarthro-dial joints. It has a world-wide incidence of approximately four per 10000 in the population aged greater than 15 years, and causes significant increases in morbidity and even mortality in affected patients [2–4]. 150 000 patients are diagnosed with RA each year in the United States at a cost of approximately $ 30 000 per case [5]. Women are twice as likely to be affected as men, and the prevalence increases with age. Although the prevalence of RA varies across the globe, no etiologic agents have been unequivocally identified [6–9].
Keywords
- Rheumatoid Arthritis
- Gene Therapy
- Reverse Transcriptase Polymerase Chain Reaction
- Gene Therapy Trial
- Rheumatoid Joint
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Muzzonigro, T.S., Kang, R., Reinecke, J., Wehling, P., Wasko, M.C., Herndon, J.H. (2000). Gene therapy for rheumatoid arthritis: clinical studies. In: Evans, C.H., Robbins, P.D. (eds) Gene Therapy in Inflammatory Diseases. Progress in Inflammation Research. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-8478-5_4
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DOI: https://doi.org/10.1007/978-3-0348-8478-5_4
Publisher Name: Birkhäuser, Basel
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