Skip to main content

Ionisation Chamber Measurements of I123 Using a Copper Filter

  • Chapter
Book cover Radioactive Isotopes in Clinical Medicine and Research

Part of the book series: Advances in Pharmacological Sciences ((APS))

Summary

The low energy X-ray emissions of 123I lead to large variations in activity measurements using an ionisation chamber. A copper filter 0.5mm thick removes these X-rays but only reduces the 159 keV emissions by 14%. However the ionisation chamber needs to be recalibrated for the copper filter attenuation. We outline a simple method using a measurement made on 99Tcm to determine the change in sensitivity of the ionisation chamber using the copper filter. With the copper filter, the variation of activity measurements when 123I is in a syringe compared to those in a vial is reduced from 80% to 3%. The ratio of the manufacturers stated activity to measured activity was 102% and 111% for two manufacturers respectively.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Harris CC, Jaszczak RJ, Greer KL, Briner WH, Coleman RE. Effect of characteristic X-Rays on Assay of I-123 by Dose Calibrator. J Nucl Med 1984; 25: 1367–1370.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1997 Springer Basel AG

About this chapter

Cite this chapter

Thomson, W.H., Hesslewood, S.R., Hepplewhite, J., Parker, K., Perrin, B. (1997). Ionisation Chamber Measurements of I123 Using a Copper Filter. In: Bergmann, H., Kroiss, A., Sinzinger, H. (eds) Radioactive Isotopes in Clinical Medicine and Research. Advances in Pharmacological Sciences. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-7772-5_34

Download citation

  • DOI: https://doi.org/10.1007/978-3-0348-7772-5_34

  • Publisher Name: Birkhäuser, Basel

  • Print ISBN: 978-3-0348-7774-9

  • Online ISBN: 978-3-0348-7772-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics