Skip to main content

Tc-99m-Sestamibi Whole Body Scintigraphy: An Useful Tool in the Follow up of Patients with Differentiated Thyroid Carcinoma?

  • Chapter
  • 126 Accesses

Part of the book series: Advances in Pharmacological Sciences ((APS))

Summary

Purpose of this study was to assess the clinical value of sestamibi whole body scintigraphy in detecting local recurrences and metastases in patients with differentiated thyroid carcinoma and to compare these results with diagnostic 131-radioiodine scans and serum thyroglobulin determinations. 75 patients — following all total thyroidectomy and high dosed radioiodine therapy — underwent sestamibi and diagnostic iodine scintigraphy. In addition, serum thyroglobulin levels were determined. Only patients with elevated thyroglobulin levels showed positive sestamibi and/or iodine uptake. In comparison with iodine scans sestamibi scintigraphy revealed with a higher sensitivity recurrences and metastases especially in follicular and Htirthle cell carcinoma.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Aktolun C., Bayhan H.,Kir M. Clinical experience with 99m-Tc-MIBI imaging in patients with malignant tumors: preliminary results and comparison with 201-thallium. Clin Nucl Med 1992: 17: 171–176

    Article  PubMed  CAS  Google Scholar 

  2. Balone HR. Fink-Benett D, Stoffer SS. 99mTechnetium-sestamibi uptake by recurrent Hürthle cell carcinoma of the thyroid. J Nucl Med 1992; 33: 1393–1395

    Google Scholar 

  3. Dadparvar S.,Kirshna L.,Brady LW, et al. The role of 131-iodine-Na and 201-thallium imaging and serum thyroglobulin in the management of differentiated thyroid carcinoma. Cancer 1993; 71: 3767–3773

    Article  PubMed  CAS  Google Scholar 

  4. Aktolun C., Bayhan H.,Kir M. Clinical experience with 99m-Tc-MIBI imaging in patients with malignant tumors: preliminary results and comparison with 201-thallium. Clin Nucl Med 1992: 17: 171–176

    Article  Google Scholar 

  5. Dadparvar S, Chevres A, Tulchinsky M, Kirshna-Badrinath L, Khan a, Slizofski W.Clinical utility of Tc-99m methoxisobutylisonitrile imaging in differentiated thyroid carcinoma: comparison with thallium-201 and iodine-131 Na scintigraphy, and serum thyroglobulin quantitation. Eur J Nucl Med 1995; 22: 1330–1338

    Article  PubMed  CAS  Google Scholar 

  6. Lastoria S, Vergara E, Varrella P, et al. Imaging of differentiated thyroid tumors with99m Tc (V) DMSA J Nucl Med 1993; 34: 12 p

    Google Scholar 

  7. Ramanna L, Waxman A, Braunstein G. 201 Thallium scintigraphy in differentiated thyroid cancer: comparison with radioiodine scintigraphy and serum determinations. J Nucl Med 1991; 32: 441–446

    PubMed  CAS  Google Scholar 

  8. Wackers FJT, Berman DS, Maddahi J, et al. 99m Technetium hexakis 2 methoxyisobutyl isonitrile: human biodistribution, dosimetry, safety, and preliminary comparison to 201-thallium for myocardial perfusion imaging. J Nucl Med 1989; 30: 301–311

    PubMed  CAS  Google Scholar 

  9. Waxman AD. Non-cardiac uses of 201-thallium and 99m-Tc-sestamibi. Clinical nuclear medicine. Harvard Medical School Annual Lectureship, 1994, p86–86

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1997 Springer Basel AG

About this chapter

Cite this chapter

Meyer, G., Kleine, U., Tiling, R., Stein, K., Hahn, K. (1997). Tc-99m-Sestamibi Whole Body Scintigraphy: An Useful Tool in the Follow up of Patients with Differentiated Thyroid Carcinoma?. In: Bergmann, H., Kroiss, A., Sinzinger, H. (eds) Radioactive Isotopes in Clinical Medicine and Research. Advances in Pharmacological Sciences. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-7772-5_11

Download citation

  • DOI: https://doi.org/10.1007/978-3-0348-7772-5_11

  • Publisher Name: Birkhäuser, Basel

  • Print ISBN: 978-3-0348-7774-9

  • Online ISBN: 978-3-0348-7772-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics