Abstract
The main applications for DNA profiling in domestic animals are identity and parentage control. Additional DNA-based tests are available for the diagnosis of genetic diseases and for the sexing of animals. The recent development of medium-density genetic linkage maps permits even initial mapping projects in domestic animal flocks (for a review see [1]). In horses, as well as other farm animals, selective breeding (e.g. for speed or jumping ability) requires exact lineage records. Therefore, spot-check parentage control is used extensively by most breed registries for a defined percentage (1–10%) of offspring from each year. Additional options used by some organizations are to test all offspring produced by artificial insemination and all males whose semen is collected for sale. The price of descendants is determined in part by the reputation of the lineage or the breeding value, thus assuring that the owner has a strong interest in establishing the correct breeding lines. In some special cases (e.g. questionable practices) the owner itself submits animals for testing. Parentage control in animals has relied on conventional testing methods [blood groups, serum proteins, red cell enzymes, major histocompatibility complex (MHC)] for several decades now. For obvious reasons (degree of polymorphism, standardization potential etc.) these methods are being replaced by more modern ones such as DNA fingerprinting or usage of microsatellites.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Buitkamp J, Epplen JT (1996) Modern genome research and DNA diagnostic in domestic animals in the light of classical breeding techniques. Electrophoresis 17: 1–11
Crooijmans RP, van Oers PA, Strijk JA, van der Poel JJ, Groenen MA (1996) Preliminary linkage map of the chicken (Gallus domesticus) genome based on microsatellite markers: 77 new markers mapped. Poult Sci 75: 746–754
Cheng HH (1997) Mapping the chicken genome. Poult Sci 76:1101–1107
Barendse W, Vaiman D, Kemp SJ, Sugimoto Y, Armitage SM, Williams JL, Sun HS, Eggen A, Agaba M, Aleyasin SA et al (1997) A medium-density genetic linkage map of the bovine genome. Mamm Genome 8:21–28
Archibald AL, Haley CS, Brown JF, Couperwhite S, Mcqueen HA, Nicholson D, Coppieters W, Vandeweghe A, Stratil A, Wintero AK et al (1995) The PiGMaP consortium linkage map of the pig (Sus scrofa). Mamm Genome 6:157–175
Rohrer GA, Alexander LJ, Keele JW, Smith TP, Beattie CW (1994) A microsatellite linkage map of the porcine genome. Genetics 136: 231–245
Andersson L, Haley CS, Ellegren H, Knott SA, Johansson M et al (1994) Genetic mapping of quantitative trait loci for growth and fatness in pigs. Science 263: 1771–1774
Knott SA, Marklund L, Haley CS, Andersson K, Davies W, Ellegren H, Fredholm M, Hansson I, Hoyheim B, Lundstrom K, Moller M, Andersson L (1998) Multiple marker mapping of quantitative trait loci in a cross between outbred wild boar and large white pigs. Genetics 149: 1069–1080
Georges M, Nielsen D, Mackinnon M, Mishra A, Okimoto R, Pasquino AT, Sargent LS, Sorensen A, Steele MR, Zaho X et al (1995) Mapping of quantitative trait loci controlling milk production in dairy cattle by exploiting progeny testing. Genetics 139: 907–920
Georges M, Lathrop M, Dietz AB, Libert F, Mishra A, Nielsen D, Sargeant LS, Steele MR, Zhao X, Leipold H et al (1993) Microsatellite mapping of the gene causing weaver disease in cattle will allow the study of an associated quantitative trait locus. Proc Natl Acad Sci USA 90: 1058–1062
Grobet L, Martin LJ, Poncelet D, Pirottin D, Brouwers B, Riquet J, Schoeberlein A, Dunner S, Menissier F, Massabanda J et al (1997) A deletion in the bovine myostatin gene causes the double-muscled phenotype in cattle. Nature Genet 17: 71–74
Marklund S, Ellegren H, Eriksson S, Sandberg K, Andersson L (1994) Parentage testing and linkage analysis in the horse using a set of highly polymorphic microsatellites. Anim Genet 25:19–23
Bowling AT, Eggleston-Stott ML, Byrns G, Clark RS, Dileanis S, Wictum E (1997) Validation of microsatellite markers for routine horse parentage testing. Anim Genet 28: 247–252
Miller SA, Dykes D, Polesky H (1988) A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16:1215
Lien S, Rogne S, Brovold MJ, Aleström P (1990) A method for isolation of DNA from frozen (A.I.) bulls semen. J Anim Breed Genet 107: 74
Jamieson A, Taylor SCS (1997) Comparisons of three probability formulae for parentage exclusion. Anim Genet 28: 397–400
Wimmers K, Weber J, Woostmann S, Wagner V, Olek K, Schellander K. (1997) Allelfrequenzen von Mikrosatellitenmarkern des internationalen Standards zur Abstammungsbegutachtung in deutschen Pferdepopulationen. In: Vortragstagung der DGfZ / GfT 1997, Bonn, B03
van Haeringen H, Bowling AT, Stott ML, Lenstra JA, Zwaagstra KA (1994) A highly polymorphic horse microsatellite locus: VHL20. Anim Genet 25: 207
Ellegren H, Johansson M, Sandberg K, Andersson L (1992) Cloning of highly polymorphic microsatellites in the horse. Anim Genet 23:133–142
Binns MM, Holmes NG, Holliman A, Scott AM (1995) The identification of polymorphic microsatellite loci in the horse and their use in thoroughbred parentage testing. Br Vet J 151: 9–15
Guerin G, Bertaud M, Amigues Y (1994) Characterization of seven new horse microsatellites — Hms1, Hms2, Hms3, Hms5, Hms6, Hms7 and Hms8. Anim Genet 25: 62
Coogle L, Bailey E, Reid R, Russ M (1996) Equine dinucleotide repeat polymorphisms at loci LEX002, -003, -004, — 005, -007, -008, -009, -010, -011, -013 and -014. Anim Genet 27:126–127
Eggleston-Stott ML, DelValle A, Bautista M, Dileanis S, Wictum E, Bowling AT (1997) Nine equine dinucleotide repeats at microsatellite loci UCDEQ136, UC-DEQ405, UCDEQ412, UCDEQ425, UC-DEQ437, UCDEQ467, UCDEQ487, UC-DEQ502 and UCDEQ505. Anim Genet 28: 370–371
Breen M, Lindgren G, Binns MM, Norman J, Irvin Z, Bell K, Sandberg K, Ellegren H (1997) Genetical and physical assignments of equine microsatellites; first integration of anchored markers in horse genome mapping. Mamm Genome 8: 267–273
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1999 Birkhäuser Verlag
About this chapter
Cite this chapter
Buitkamp, J., Antes, R., Wagner, V. (1999). DNA Profiling in Veterinary Medicine. In: Epplen, J.T., Lubjuhn, T. (eds) DNA Profiling and DNA Fingerprinting. Methods and Tools in Biosciences and Medicine. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-7582-0_4
Download citation
DOI: https://doi.org/10.1007/978-3-0348-7582-0_4
Publisher Name: Birkhäuser, Basel
Print ISBN: 978-3-7643-6018-4
Online ISBN: 978-3-0348-7582-0
eBook Packages: Springer Book Archive