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ACE Inhibitors pp 29–36Cite as

Birkhäuser

Crosstalk between ACE inhibitors, B2 kinin receptor and nitric oxide in endothelial cells

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Part of the book series: Milestones in Drug Therapy MDT ((MDT))

Abstract

The endothelium is an important target organ of angiotensin converting enzyme (ACE) inhibitors. Within these monolayered cells establishing the interface between blood and vasculature, a complex signal transduction machinery is the basis for a major role of ACE inhibition in the regulation of vascular homoestasis. This chapter will focus on the endothelial aspects of ACE-inhibition, on its interaction with components of the kallikrein-kinin system.

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Author information

Authors and Affiliations

  1. Disease Groups Research, Aventis Pharma Deutschland GmbH, Building H821, D-65926, Frankfurt/Main, Germany

    Paulus Wohlfart, Gabriele Wiemer, Wolfgang Linz & Bernward A. Schölkens

Authors
  1. Paulus Wohlfart
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  2. Gabriele Wiemer
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  3. Wolfgang Linz
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  4. Bernward A. Schölkens
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Editor information

Editors and Affiliations

  1. Department of Pharmacology, Institute of Pharmacology of Sherbrooke, Medical School, Sherbrooke University, J1H-5N4, Sherbrooke, PQ, Canada

    Pedro D’Orléans-Juste  & Gérard E. Plante  & 

  2. Departments of Medicine (Nephrology), Physiology and Pharmacology, Institute of Pharmacology, University of Sherbrooke, Sherbrooke, Québec, Canada

    Gérard E. Plante

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© 2001 Birkhäuser Verlag/Switzerland

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Wohlfart, P., Wiemer, G., Linz, W., Schölkens, B.A. (2001). Crosstalk between ACE inhibitors, B2 kinin receptor and nitric oxide in endothelial cells. In: D’Orléans-Juste, P., Plante, G.E. (eds) ACE Inhibitors. Milestones in Drug Therapy MDT. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-7579-0_3

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  • DOI: https://doi.org/10.1007/978-3-0348-7579-0_3

  • Publisher Name: Birkhäuser, Basel

  • Print ISBN: 978-3-0348-7581-3

  • Online ISBN: 978-3-0348-7579-0

  • eBook Packages: Springer Book Archive

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