Antioxidant status (selenium, vitamins A and E) and aging

  • M. Simonoff
  • C. Sergeant
  • N. Garnier
  • P. Moretto
  • Y. Llabador
  • G. Simonoff
  • C. Conri
Part of the EXS book series (EXS, volume 62)


Antioxidant status can be evaluated by blood selenium, vitamins A and E. The level of selenium was determined in whole blood, erythrocytes and plasma of 170 French people (70–95 years old) healthy and with intercurrent illness, by using PIXE (proton-induced X-ray emission analysis). These results are discussed with other values from the literature. Plasma levels of vitamins A and E have been measured by HPLC. All data were compared with those obtained for younger subjects. Healthy elderly people residing in a geriatric home received selenium supplements during 1 month. The influence of this supplementation brought to light a deficiency for this trace element. The correlation of aging and nutritional requirements with immune function, heart and cancer death rate is presented and discussed.


Selenium Level Selenium Deficiency Serum Selenium Selenium Status Keshan Disease 
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Copyright information

© Birkhäuser Verlag Basel/Switzerland 1992

Authors and Affiliations

  • M. Simonoff
    • 1
    • 2
  • C. Sergeant
    • 1
    • 2
  • N. Garnier
    • 1
    • 2
  • P. Moretto
    • 1
    • 2
  • Y. Llabador
    • 1
    • 2
  • G. Simonoff
    • 1
    • 2
  • C. Conri
    • 1
    • 2
  1. 1.Centre d’Etudes Nucléaires de Bordeaux-GradignanGradignan, CedexFrance
  2. 2.Médecine Interne et CardiologieHôpital St André 1Bordeaux, CedexFrance

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