Age-related variations of enzymatic defenses against free radicals and peroxides

  • Yves Artur
  • Bernard Herbeth
  • Laila Guémouri
  • Edith Lecomte
  • Claude Jeandel
  • Gérard Siest
Part of the EXS book series (EXS, volume 62)


Superoxide dismutase, glutathione peroxidase and catalase are the three main enzymatic systems of defense of the organism against free radicals and peroxides. A survey of the literature shows that no general tendency of evolution of these systems in aging emerges, even if some recent studies in humans demonstrate the existence of a concomitant decrease in most of the antioxidant enzymes in blood of the elderly. The study of the antioxidant systems and their interrelations in the elderly represents a large field of future investigations.


Antioxidant Enzyme Superoxide Dismutase Glutathione Peroxidase Antioxidant Enzyme Activity Free Radical Theory 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Birkhäuser Verlag Basel/Switzerland 1992

Authors and Affiliations

  • Yves Artur
    • 1
  • Bernard Herbeth
    • 1
    • 2
  • Laila Guémouri
    • 1
  • Edith Lecomte
    • 1
  • Claude Jeandel
    • 3
  • Gérard Siest
    • 1
  1. 1.Centre de Médecine PréventiveVandoeuvre-lès-NancyFrance
  2. 2.Faculté de MédecineINSERM U115Vandoeuvre-lès-NancyFrance
  3. 3.Service de Médecine Interne BCentre Hospitalier Régional UniversitaireVandoeuvre-lès-NancyFrance

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