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Effect of Nicotine on Red Cell Deformabilitiy in Diabetes Mellitus

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Book cover Effects of Nicotine on Biological Systems

Part of the book series: APS Advances in Pharmacological Sciences ((APS))

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Summary

Red blood cell (RBC) deformability was assessed by using microfiltration technique and expressed in terms of filtration time of 0.5 ml of 20% erythrocyte suspension. The mean filtration time of diabetic group was 35.5% longer than that of control group. Nicotine (10−5 −10−2 M) produced biphasic alterations in filtration times of both control and diabetic erythrocytes. An initial increase was followed by a slight but significant decrease. The extents of these alterations were concentration-dependent and greater in diabetic group.

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Author information

Authors and Affiliations

  1. Department of Cardiology, Medical School of Ankara University, Ankara, Turkey

    K. Salbaş, V. Ulusoy & T. Akyol

  2. Cardiology Research Center, Medical School of Ankara University, Ankara, Turkey

    K. Salbaş, V. Ulusoy & T. Akyol

Authors
  1. K. Salbaş
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  2. V. Ulusoy
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  3. T. Akyol
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Editor information

Editors and Affiliations

  1. Forschungsrat Rauchen und Gesundheit, Königswinterer Straße 550, D-W-5300, Bonn 3, Germany

    Franz Adlkofer M.D. (Professor of Medicine, Scientific Secretary of the Research Council on Smoking and Health) (Professor of Medicine, Scientific Secretary of the Research Council on Smoking and Health)

  2. Physiologisches Institut, Universität München, Pettenkofer Straße 12, D-W-8000, München 2, Germany

    Klaus Thurau M.D. (Professor of Physiology, Chairman of the Research Council on Smoking and Health) (Professor of Physiology, Chairman of the Research Council on Smoking and Health)

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© 1991 Birkhäuser Verlag Basel

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Salbaş, K., Ulusoy, V., Akyol, T. (1991). Effect of Nicotine on Red Cell Deformabilitiy in Diabetes Mellitus. In: Adlkofer, F., Thurau, K. (eds) Effects of Nicotine on Biological Systems. APS Advances in Pharmacological Sciences. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7457-1_31

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  • DOI: https://doi.org/10.1007/978-3-0348-7457-1_31

  • Publisher Name: Birkhäuser Basel

  • Print ISBN: 978-3-0348-7459-5

  • Online ISBN: 978-3-0348-7457-1

  • eBook Packages: Springer Book Archive

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