Summary
Red blood cell (RBC) deformability was assessed by using microfiltration technique and expressed in terms of filtration time of 0.5 ml of 20% erythrocyte suspension. The mean filtration time of diabetic group was 35.5% longer than that of control group. Nicotine (10−5 −10−2 M) produced biphasic alterations in filtration times of both control and diabetic erythrocytes. An initial increase was followed by a slight but significant decrease. The extents of these alterations were concentration-dependent and greater in diabetic group.
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© 1991 Birkhäuser Verlag Basel
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Salbaş, K., Ulusoy, V., Akyol, T. (1991). Effect of Nicotine on Red Cell Deformabilitiy in Diabetes Mellitus. In: Adlkofer, F., Thurau, K. (eds) Effects of Nicotine on Biological Systems. APS Advances in Pharmacological Sciences. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7457-1_31
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DOI: https://doi.org/10.1007/978-3-0348-7457-1_31
Publisher Name: Birkhäuser Basel
Print ISBN: 978-3-0348-7459-5
Online ISBN: 978-3-0348-7457-1
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