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Serotonin, violent behavior and alcohol

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Book cover Toward a Molecular Basis of Alcohol Use and Abuse

Part of the book series: Experientia ((EXS,volume 71))

Summary

At the NIAAA intramural research program, in collaboration with investigators at the Department of Psychiatry, University of Helsinki, we have mounted an extensive research program on early onset male alcoholism. A central serotonergic deficit is common among these patients. This finding has led to behavioral, biochemical, physiological and molecular genetic studies on the serotonin system in early onset, antisocial and violent male alcoholics and in appropriate control populations. The results of the studies completed by the fall of 1993 are summarized in this communication.

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Authors and Affiliations

  1. Laboratories of Clinical Studies, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland, USA

    Markku Linnoila, Matti Virkkunen, Theodore George, Michael Eckardt, James D. Higley, David Nielsen & David Goldman

  2. Laboratories of Neurogenetics, Division of Intramural Clinical and Biological Research, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland, USA

    David Nielsen & David Goldman

  3. Department of Psychiatry, University of Helsinki, Helsinki, Finland

    Matti Virkkunen

Authors
  1. Markku Linnoila
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  2. Matti Virkkunen
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  3. Theodore George
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  4. Michael Eckardt
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  5. James D. Higley
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  6. David Nielsen
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  7. David Goldman
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Editor information

Editors and Affiliations

  1. Department of Psychiatry, Karolinska Institutet, Huddinge University Hospital, S-141 86, Huddinge, Sweden

    B. Jansson

  2. Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-171 77, Stockholm, Sweden

    H. Jörnvall

  3. Department of Clinical Neuroscience, Karolinska Institutet, S-171 76, Stockholm, Sweden

    U. Rydberg  & L. Terenius  & 

  4. Center for Biochemical and Biophysical Sciences and Medicine, Harvard Medical School, Seeley G. Mudd Building, 250 Longwood Avenue, 02115, Boston, MA, USA

    B. L. Vallee

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© 1994 Birkhäuser Verlag Basel/Switzerland

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Linnoila, M. et al. (1994). Serotonin, violent behavior and alcohol. In: Jansson, B., Jörnvall, H., Rydberg, U., Terenius, L., Vallee, B.L. (eds) Toward a Molecular Basis of Alcohol Use and Abuse. Experientia, vol 71. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7330-7_16

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  • DOI: https://doi.org/10.1007/978-3-0348-7330-7_16

  • Publisher Name: Birkhäuser Basel

  • Print ISBN: 978-3-0348-7332-1

  • Online ISBN: 978-3-0348-7330-7

  • eBook Packages: Springer Book Archive

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