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Nonselective Cation Channels pp 121–133Cite as

Cyclic Nucleotide-Gated Nonselective Cation Channels: A Multifunctional Gene Family

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Part of the book series: EXS ((EXS,volume 66))

Abstract

The light-regulated flow of ions across the plasma membrane of vertebrate rod and cone photoreceptors passes through a nonselective cation channel that is directly gated by guanosine 3′,5′-cyclic monophosphate (cGMP). It is the purpose of this brief chapter to review the physiological and structural properties of this channel. As will be described below, these channels appear to have structural features in common with some other voltage-gated channels. Whether or not they also show structural relationships to other types of nonselective cation channels, such as those described in other chapters in this volume, remains to be determined.

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Author information

Authors and Affiliations

  1. Department of Ophthalmology and Visual Science, Yale University School of Medicine, 330 Cedar Street, New Haven, CT, 06510, USA

    Colin J. Barnstable

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  1. Colin J. Barnstable
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Editor information

Editors and Affiliations

  1. Institut für Zoologie, Universität Regensburg, Universitätsstrasse 31, D-93040, Regensburg, Germany

    Detlef Siemen

  2. Institut für Pharmakologie, Freie Universität Berlin, Thielallee 69-73, D-14195, Berlin, Germany

    Jürgen Hescheler

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© 1993 Birkhäuser Verlag Basel/Switzerland

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Barnstable, C.J. (1993). Cyclic Nucleotide-Gated Nonselective Cation Channels: A Multifunctional Gene Family. In: Siemen, D., Hescheler, J. (eds) Nonselective Cation Channels. EXS, vol 66. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7327-7_9

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  • DOI: https://doi.org/10.1007/978-3-0348-7327-7_9

  • Publisher Name: Birkhäuser Basel

  • Print ISBN: 978-3-0348-7329-1

  • Online ISBN: 978-3-0348-7327-7

  • eBook Packages: Springer Book Archive

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