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Analgesia and Addiction

  • Chapter
Fortschritte der Arzneimittelforschung / Progress in Drug Research / Progrès des recherches pharmaceutiques

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Abstract

Pain is a common experience of man and usually serves the very useful purpose of alerting him to physical danger. However, continued pain or pain produced by procedures performed intentionally for the palliation or cure of disease is undesirable and should be suppressed. It is for this purpose that the ‘pain killing’ or analgesic drugs are employed widely in modern therapy. It is an unfortunate fact that the potent1) drugs which produce analgesia are concomitantly addicting, i.e. that they produce physical and psychic dependence as well as exhibiting the phenomenon of tolerance development. After many years of concentrated search, pharmacology and medicine still seek a reliable analgesic without these undesirable side effects.

The authors are deeply indebted to Dr. Nathan B. Eddy, Chairman, Committee on Drug Addiction and Narcotics, National Research Council, Washington, D.C., and to Drs. M. H. Seevers and G. A. Deneau, Department of Pharmacology, University of Michigan Medical School, Ann Arbor, for permission to use unpublished data.

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  1. University of Michigan Medical School, Ann Arbor, Michigan, USA

    L. B. Mellett

  2. College of Medicine, State University of Iowa, Iowa City, Iowa, USA

    L. A. Woods

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  1. L. B. Mellett
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  2. L. A. Woods
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    © 1963 Birkhäuser Verlag Basel

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    Mellett, L.B., Woods, L.A. (1963). Analgesia and Addiction. In: Jucker, E. (eds) Fortschritte der Arzneimittelforschung / Progress in Drug Research / Progrès des recherches pharmaceutiques. Fortschritte der Arzneimittelforschung / Progress in Drug Research / Progrès des recherches pharmaceutiques, vol 5. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7047-4_2

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    • DOI: https://doi.org/10.1007/978-3-0348-7047-4_2

    • Publisher Name: Birkhäuser Basel

    • Print ISBN: 978-3-0348-7049-8

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