Abstract
Differential Scanning Calorimetry (DSC) is widely regarded as an important analytical tool in pharmaceutical research. It is well-known, however, that experimental factors can influence the results considerably. These factors relate to:
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The adjustment of the apparatus, such as heating rate and calorimetric sensitivity.
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The sample’s mass, packing and porosity, particle size (distributions), pretreatment and dilution.
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3.
The reference material’s mass, nature and pretreatment.
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4.
The atmosphere: thermal conductivity, oxidising or inert nature, static or flowing conditions.
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References
A. Gäumann, J. Oswald. Chimia21 (1967), 421–426
ICTA recommendations on nomenclature and reporting of thermal analysis data (1977)
H.E. Kissinger, Anal.Chem. 29 (1957), 1702 – 1706
E.M. Barrall, L.B. Rogers, Anal.Chem. 34 (1962), 1101 – 1106
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© 1980 Springer Basel AG
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van Dooren, A.A. (1980). Influence of Experimental Variables on DSC Curves. In: Wiedemann, H.G. (eds) Thermal Analysis. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-6719-1_13
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DOI: https://doi.org/10.1007/978-3-0348-6719-1_13
Publisher Name: Birkhäuser, Basel
Print ISBN: 978-3-0348-6720-7
Online ISBN: 978-3-0348-6719-1
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