Abstract
In an approach to elucidate the conformation of metallothioneins, far-ultraviolet circular dichroism was measured. Using 270 MHz proton magnetic resonance spectroscopy it was expected to characterize further the structure described by circular dichroism as unordered. In addition, the oxidation-reduction properties of yeast Cu-thionein were studied by electron paramagnetic resonance spectroscopy. The biological implications of the oxidation state of copper in Cu-thionein are discussed.
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References
Bayley, P. M. (1973) in Progress in Biophysics and Molecular Biology (Butler, J. A. V. and Noble, D., eds.), Vol.27, pp.3–76, Pergamon Press, Oxford.
Fasman, G. D., Hoving, H. and Timasheff, S. N. (1970) Biochemistry 9, 3316–3324.
Rupp, H., Voelter, W. and Weser, U. (1975) Z. Physiol. Chem. 356, 755–765.
Rupp, H. and Weser, U. (1978) Biochim. Biophys. Acta 533, 209–226
McDonald, C. C. and Phillips, W. D. (1969) J. Am. Chem. Soc. 91, 1513–1521.
Rupp, H., Voleter, W. and Weser, U. (1974) FEBS Lett. 40, 176–179.
Weser, U., Donay, F. and Rupp, H. (1973) FEBS Lett. 32, 171–173.
Weser, U., Rupp, H., Donay, F., Linnemann, F., Voelter, W., Voetsch, W. and Jung, G. (1973) Eur. J. Biochem. 39, 127–140.
Malkin, R. and Malmström, B. G. (1970) in Advances in Enzymology (Nord, F. F., ed.)33, pp.177–244, Interscience Publ., New York.
Colman, P. M., Freeman, H. C., Guss, J. H., Murata, M., Norris, V. A., Ramshaw, F. A. M. and Venkatappa, M. P. (1978) Nature 272, 319–324.
Carter, C. W. (1977) in Iron-Sulphur Proteins (Lovenberg, W., ed.) Vol.3, pp.157–204, Academic Press, New York.
Rupp, H., Rao, K. K., Hall, D. O. and Cammack, R. (1978) Biochim. Biophys. Acta, in press.
Moore, A. L. and Rupp, H. (1978) FEBS Lett. in press.
Rupp, H. and Moore, A. L., Biochim. Biophys. Acta, submitted.
Rupp. H., de La Torre, A. and Hall, D. O., Biochim. Biophys. Acta submitted.
Rupp, H. and Weser, U. (1976) Bioinorganic Chem. 6, 45–59.
Rupp, H. and Weser, U. (1976) Biochem. Biophys. Res. Commun. 72, 223–229.
Rupp, H. and Weser, U. (1976) Biochim. Biophys. Acta 446, 151–165.
Ottersen, T., Warner, L. G. and Seff, K. (1974) Inorg. Chem. 13, 1904–1911.
Kroneck, P. (1975) J. Am. Chem. Soc. 97, 3839–3841.
Makino, N., McMahill, P., Mason, H. S. and Moss, T. H. (1974) J. Biol. Chem. 249, 6062–6066.
Rupp, H. and Weser, U. (1974) FEBS Lett. 44, 293–297.
Rupp, H., Cammack, R., Hartmann, H. J. and Weser, U. Biochem. J. submitted.
Österberg, R. (1974) Nature 249, 382–383.
Supported by grants from the Deutsche Forschungsgemeinschaft (We401/14) and by NATO Res. Programme (No.1256).
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Rupp, H., Weser, U. (1979). Structural Aspects and Reduction Oxidation Reactions of Metallothionein. In: Kägi, J.H.R., Nordberg, M. (eds) Metallothionein. Experientia Supplementum, vol 34. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-6493-0_16
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DOI: https://doi.org/10.1007/978-3-0348-6493-0_16
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