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Abstract

It is clear that more thorough investigations into the mechanisms of the transfection methods for the animal virus nucleic acids are needed. Much of the work that has been done to date has been concerned primarily with devising ways of getting high infectivity titers for animal virus NA preparations, but only incidentally with bettering our understanding of the ways in which transfection methods work. It seems safe to predict that increased knowledge of the mechanisms of the transfection methods will point the way to modifications resulting in transfection methods of greater sensitivity and precision, and, perhaps in some cases, of greater selectivity.