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Frontiers in Crustacean Neurobiology pp 140–151Cite as

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Presynaptic Inhibition of Primary Afferent Synapses in the Crayfish

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Part of the book series: Advances in Life Sciences ((ALS))

Summary

Presynaptic inhibition of primary mechanoafferents in the crayfish abdomen, elicited during giant axon-mediated escape, protects primary afferent synapses from depression which would result from reafference during the tailflip. As in vertebrates, this inhibition is associated with primary afferent depolarization (PAD) ostensibly produced by a GABA-mediated increase in chloride conductance. We have physiologically and morphologically characterized the inhibitory interneurons (PADIs) directly responsible for producing PAD and presynaptic inhibition, identified elements of the pathways excited by the giant escape command cells which recruit the PADIs, and are currently studying the ultrastructure of synapses between the PADIs and afferent terminals.

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Author information

Authors and Affiliations

  1. Division of Biological Sciences, University of Missouri at Columbia, Lefevre Hall, Columbia, MO, 65211, USA

    Mark D. Kirk

  2. Life Sciences Division, Scarborough College, University of Toronto, 1265 Military Trail, Scarborough, Ontario, Canada, M1C 1A4

    C. K. Govind

Authors
  1. Mark D. Kirk
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  2. C. K. Govind
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Editor information

Editors and Affiliations

  1. Zoologisches Institut, Universität Hamburg, Martin-Luther-King Platz 3, D-2000, Hamburg 13, Germany

    K. Wiese

  2. Zoologisches Institut, Universität Basel, Rheinsprung 9, CH-4051, Basel, Switzerland

    W.-D. Krenz

  3. Fakultät für Biologie, Universität Konstanz, Postfach 5560, D-7750, Konstanz, Germany

    J. Tautz

  4. Laboratoire de Neurobiologie, Département de Biologie Animale, Université de Genève, 20, rue Ecole de Médecine, CH-1211, Genève 4, Switzerland

    H. Reichert

  5. Zoology Department, University of California at Davis, 95616, Davis, CA, USA

    B. Mulloney

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© 1990 Springer Basel AG

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Kirk, M.D., Govind, C.K. (1990). Presynaptic Inhibition of Primary Afferent Synapses in the Crayfish. In: Wiese, K., Krenz, WD., Tautz, J., Reichert, H., Mulloney, B. (eds) Frontiers in Crustacean Neurobiology. Advances in Life Sciences. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-5689-8_15

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  • DOI: https://doi.org/10.1007/978-3-0348-5689-8_15

  • Publisher Name: Birkhäuser, Basel

  • Print ISBN: 978-3-0348-5691-1

  • Online ISBN: 978-3-0348-5689-8

  • eBook Packages: Springer Book Archive

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