Abstract
It has been established that plasma unesterified long chain fatty acids (FFA) are a major substrate used as an energy source by skeletal muscle during prolonged submaximal activity [5, 6, 19, 24]. The ability of the muscle to take advantage of this potential energy depends upon the capacity to activate, transport and oxidize these intramuscular FFA molecules. The responses of the enzymes of fatty acid activation, transport and oxidation to a single bout of prolonged electrical stimulation were examined in order to better assess the potential of in situ skeletal muscle to utilize FFA to fulfill acutely imposed metabolic demands. To this end, the activities of the enzymes ATP dependent palmitoyl CoA-synthetase (EC 6.2. 1–3) carnitine palmitoyl transferase (EC 2.3.1.-) 3 hydroxyacyl — CoA dehydrogenase (EC 1.1–1–35) and acetyl — CoA acyl transferase (EC 2–3–1–16) were measured following forty-five minutes of direct electrical stimulation.
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Saville, W.A., Edington, D.W. (1975). The Effect of Prolonged Direct Electrical Stimulation upon the Enzymes of Fatty Acid Activation, Transport and Oxidation in Rat Skeletal Muscle. In: Howald, H., Poortmans, J.R. (eds) Metabolic Adaptation to Prolonged Physical Exercise. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-5523-5_56
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DOI: https://doi.org/10.1007/978-3-0348-5523-5_56
Publisher Name: Birkhäuser, Basel
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