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The Role of Inflammation in Lymphoma

Chapter
First Online:
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 816)

Abstract

Human lymphomas usually develop in specialized tissue microenvironments characterized by different populations of accessory stromal and lymphoid cells that interact with malignant cells. A clinical role of the tumor microenvironment has recently emerged, bringing new knowledge and suggesting new ideas and targets for treatment. This chapter analyzes the microenvironment in human lymphomas highlighting the role of inflammation in their pathogenesis. Microenvironmental specificity is detailed according to different models including classic Hodgkin lymphoma (HL), follicular lymphoma (FL), diffuse large B-cell lymphoma (DLBCL), peripheral T-cell lymphoma, unspecified and angioimmunoblastic T-cell lymphoma (AITL).

Keywords

Follicular Lymphoma Brentuximab Vedotin Classic Hodgkin Lymphoma Lymphomatoid Granulomatosis Human Lymph Node 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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© Springer Basel 2014

Authors and Affiliations

  1. 1.Department of Pathology, Centro di Riferimento Oncologico AvianoIstituto Nazionale Tumori, IRCCSAvianoItaly
  2. 2.Tumor Immunology Unit, Human Pathology Section, Department of Health SciencesUniversity of PalermoPalermoItaly
  3. 3.Department of Oncology and Hematology, Humanitas Cancer CenterHumanitas Clinical and Research CenterRozzanoItaly
  4. 4.Department of Diagnostic Pathology and Laboratory MedicineFondazione IRCCS Istituto Nazionale dei TumoriMilanoItaly

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