Abstract
In this chapter, the authors will focus on current and, especially, future technological transformations in medicine during the final phase of the Cybernetic Revolution. Medicine is and will be a branch around which different technologies (AI, robots, 3d-printing, bio, nano and cognitive technologies) combine. The present chapter provides more examples of such interrelationships denoted by the authors as MANBRIC-complex. Grinin et al. argue that there is a wide range of prospects for the development of medicine in the twenty-first century. The general vector of breakthroughs makes it possible to expand our ability to modify the human body and genome. These changes will probably include the following: the expansion of the opportunities to perform minimally invasive operations instead of the current surgical ones; the cultivation of specific biological materials, body parts and other elements for the regeneration and rehabilitation of an organism, as well as artificial analogues of biological materials (tissues, bodies, receptors, etc.) and so on. Along with the achievements that have been and will be made in medicine, the authors will also identify a number of serious problems and challenges, such as the increasing medicalization of humans and the current stagnation in the pharmaceutical industry.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Notes
- 1.
The recent archaeological discovery made in a cave in Borneo, Indonesia, completely changes our understanding of the Stone Age: the scientists found an amputee who lived 31,000 years ago. Meanwhile, just two hundred years ago, many people who had limbs amputated died either from blood loss and shock, or from infection (Prillaman 2022).
- 2.
When preparing the paragraph on surgery, we used data from Petrov 2014.
- 3.
- 4.
- 5.
The opioid overdose deaths in the USA increased to 75,673 in the 12-months ending in April 2021, from 56,064 the year before (NCHS, 2021). The opioid overdose deaths continue to rise rapidly.
- 6.
It is obvious that the mass-market drugs have a significant disadvantage: their effectiveness decreases and they help only some patients, whose number can range between 30 to 50 percent (Martyushev-Poklad 2015). Medication errors also cause serious side effects. For example, according to some data (probably, overestimated), the prescription errors caused more than 100,000 deaths per year in the late 1990s and early 2000s (Null et al., 2004: Table 1). Medical errors are quite costly to society. For example, medical billing errors cost Americans $210 billion annually. Approximately 12 million Americans are misdiagnosed every year. And it is estimated that 7,000 to 9,000 patients die every year from medication errors (Medical Error Statistics 2022).
- 7.
As we discussed in Chap. 7, the characteristics of a healthy life are also expressed in the Healthy Life Expectancy (HALE) index, which (according to the WHO methodology) takes into account years of life lost due to premature mortality and years lived with poor state of health (Disability Adjusted Life Years, DALY) (see Murray et al., 2002, 2012; Murray & Lopez, 2013; Wang et al., 2012; Sindyashkina, 2022).
- 8.
This will be discussed further in Chap. 10; in particular, we will speak about robots that can replace junior medical staff in caring for the sick, old and infirm.
- 9.
It is a large machine which is equipped with flexible ‘hands’—manipulators with a set of surgical tools. A very small incision is made in the patient; therefore the operations are less painful and patients need a shorter period for recovery. Robots can use all the latest tele-video systems which allow doctors to see the operation clearly, magnified and in color. The doctor watches the monitor and controls the robot, sitting in the other part of the surgery (in the future he could also be in any other city or even country), the assistant watches the robot and the patient. For the purpose of watching the surgery process in full detail, the HD 3D screens are installed. Robot-assisted surgeries are becoming very popular, for example, the medical companies in the USA use the billboards to attract more clients to these painless fast procedures (Pinkerton 2013).
- 10.
- 11.
Russian scientists are developing a new method for treating liver cirrhosis. It involves placing a cellular scaffold made of a special porous material—air gel—in place of the removed diseased part of the organ. It will trigger cell regeneration and help the body repair damaged tissue (Gritsenko & Maleva, 2023).
- 12.
- 13.
Once a sufficient number of cells have been grown, they are implanted in the developed materials, which are based on polysaccharides and special substrates which control their growth. The growth conditions of the cells in these structures are very similar to their natural environment.
- 14.
It proves once again the point which was made 200 years ago by the founder of vaccines, Edward Jenner, ‘The deviation of man from the state in which he was originally placed by nature seems to have proved to him a prolific source of diseases.’.
- 15.
It is difficult to say how ‘perfect’ they will be and what kind of problems will as a result of these technologies. For example, the ability to predict a baby’s gender has resulted in gender imbalance in China. As a result, there is a disproportionate number of boys.
- 16.
On the achievement of superhuman abilities through genetic engineering technologies, see also the conclusion to this chapter.
- 17.
In addition to these anti-aging technologies, we also highlight: 1) drugs (geroprotectors, “drugs for old age”); 2) technologies of regeneration, substitution/cyborgization (organ replacement, cultivation of organs and tissues; transplantation of intestinal biota); 3) genetic engineering technologies and a number of others. In Chap. 11, we describe in detail these and other emerging technologies for combating aging, rejuvenating the body, and their prospects.
- 18.
- 19.
One of today’s optogenetic technologies provides a good example and a general idea of how this can work. The essence of the technology is that a fragment of DNA which encodes specific membrane proteins is integrated into the genome. These light-activated proteins (from the light source implanted in the brain tissue or through transosseous luminescence) can create an ion flow inside the cell and thus lead to its activation (Saigitov, 2015).
References
Agate, S., Argyropoulos, D. S., Jameel, H., Lucia, L., & Pal, L. (2020). 3D Photoinduced spatiotemporal resolution of cellulose-based hydrogels for fabrication of biomedical devices. ACS Applied Bio Materials, 3(8), 5007–19.
Alemzadeh, H., Raman, J., Leveson, N., Kalbarczyk, Z., & Iyer, R. K. (2016). Adverse events in robotic surgery: A retrospective study of 14 Years of FDA data. PLoS ONE, 11(4), e0151470. https://doi.org/10.1371/journal.pone.0151470
Amadei, G., Handford, Ch. E., Qiu, Ch., De Jonghe, J., Greenfeld, H., Tran, M., & Martin, B. K. et al. (2022). Synthetic embryos complete gastrulation to neurulation and organogenesis. Nature, August 25, 1–3. https://doi.org/10.1038/s41586-022-05246-3.
Armour, B. S., Courtney-Long, E. A., Fox, M. H., Fredine, H., & Cahill, A. (2016). Prevalence and causes of paralysis—United States, 2013. American Journal of Public Health, 106(10), 1855–1857. https://doi.org/10.2105/AJPH.2016.303270
Arnum, P. Van. (2022). New drug approvals in 2021: The numbers and trends. DCAT Value Chain Insights. https://www.dcatvci.org/features/new-drug-approvals-in-2021-the-numbers-and-trends/.
Bajaj, S. (2022). Why did the first human patient to receive a pig heart transplant die? Smithsonian Magazine. https://www.smithsonianmag.com/science-nature/why-exactly-did-the-first-human-patient-to-receive-a-pig-heart-die-180980361/.
Barret, J. P., Gavaldà, J., Bueno, J., Nuvials, X., Pont, T., Masnou, N., Colomina, M. J., Serracanta, J., Arno, A., & Huguet, P. (2011). Full face transplant: The first case report. Annals of Surgery, 254(2), 252–256.
Blasco-Fontecilla, H. (2014). Medicalization, wish-fulfilling medicine, and disease mongering: toward a brave new world? Revista Clinica Espanola, 214(2), 104–107.
BrandEssence. (2020). Medical aesthetics market size, share, scope, trends, and industry growth analysis by 2027. Report Analysis 2021–2027. Brand Essence® Market Research and Consulting. https://brandessenceresearch.com/medical-device/medical-aesthetics-market.
Brown, K. (2000). The human genome business today. Scientific American, 282(1), 50–55.
Browne, Ed. (2022). The Story of He Jiankui, Now Out of Jail After Editing DNA of Unborn Babies. Newsweek, April 11.https://www.newsweek.com/he-jiankui-out-jail-editing-genome-dna-unborn-babies-crispr-1696846.
Bush, E. (2022). Pig heart transplants in humans show signs of success. NBC News, https://www.nbcnews.com/science/science-news/pig-heart-transplants-humans-show-signs-success-rcna37672.
Businesswire. (2022). 3DBio therapeutics and the microtia-congenital ear deformity institute conduct human ear reconstruction using 3D-bioprinted living tissue implant in a first-in-human clinical trial. Businesswire, June 2. https://www.businesswire.com/news/home/20220602005051/en/3DBio-Therapeutics-and-the-Microtia-Congenital-Ear-Deformity-Institute-Conduct-Human-Ear-Reconstruction-Using-3D-Bioprinted-Living-Tissue-Implant-in-a-First-in-Human-Clinical-Trial.
Cavalcanti, A., Shirinzadeh, B., Zhang, M., & Kretly, L. C. (2008). Nanorobot hardware architecture for medical defense. Sensors, 8(5), 2932–2958.
CBS. (2017). Exclusive: Doctors perform heart surgery on baby still inside womb to remove tumor. https://www.cbsnews.com/philadelphia/news/chop-doctors-fetal-heart-surgery/.
Centers for Disease Control and Prevention and The Merck Company Foundation. (2007). The state of aging and health in America 2007. Whitehouse Station, NJ: The Merck Company Foundation. chrome-extension: //efaidnbmnnnibpcajpcglclefindmkaj/https://www.cdc.gov/aging/pdf/saha_2007.pdf
Chen, S. (2022). Chinese scientists create AI nanny to look after embryos in artificial womb. South China Morning Post, https://www.scmp.com/news/china/science/article/3165325/chinese-scientists-create-ai-nanny-look-after-babies-artificial.
Chi, J., Wu, Y., Qin, F., Su, M., Cheng, N., Zhang, J., & Li, C. et al. (2022). All-printed point-of-care immunosensing biochip for one drop blood diagnostics. Lab on a Chip, 22, 16, August 9, 3008–14. https://doi.org/10.1039/D2LC00385F.
Chumakov, A. N., & Yurchenko, P. S. (2021). Global pandemic in terms of objective causes and subjective speculations. Journal of Globalization Studies, 12(2), 157–168.
Cleveland Clinic. (2021). Surgery on baby in womb removes life-threatening tumor on heart. Cleveland Clinic. https://my.clevelandclinic.org/patient-stories/534-surgery-on-baby-in-womb-removes-life-threatening-tumor-on-heart.
Clinical Research Fastrack. (2020). Growth of clinical trials. Clinical Research Fastrack. https://clinicalresearchfastrack.com/growth-of-clinical-trials/.
Conrad, P. (1992). Medicalization and social control. Annual Review of Sociology, 209–32.
Conrad, P. (2005). The shifting engines of medicalization. Journal of Health and Social Behavior, 46(1), 3–14.
Crew, B. (2020). Worth the cost? A closer look at the Da Vinci Robot’s impact on prostate cancer surgery. Nature, 580(7804), S5–7. https://doi.org/10.1038/d41586-020-01037-w.
Demirel, P., & Mazzucato, M. (2008). The evolution of firm growth dynamics in the us pharmaceutical industry: Is ‘Structure’ in the growth process related to size and location dynamics? IKD Working Paper, 38(9), 1–28.
Denisova, I. V. (2021). Sdelay menya tochno. Kak reproduktivnyye tekhnologii menyayut mir. Individuum.
Dickert, F. L., Hayden, O., & Halikias, K. P. (2001). Synthetic receptors as sensor coatings for molecules and living cells. The Analyst, 126, 766–771.
Efremov, I., & Arkhangelsky, V. (2023). Global fertility changes in the context of the COVID-19 Pandemic. Journal of Globalization Studies, 14(2), 165–170.
Elrod, J. K., & Fortenberry, J. L. (2017). Centers of excellence in healthcare institutions: What they are and how to assemble them. BMC Health Services Research, 17(1), 15–24.
ESMO. (2018). Man against machine: Artificial intelligence is better than dermatologists at diagnosing skin cancer. Annals of Oncology Press Release. https://www.esmo.org/newsroom/press-releases/artificial-intelligence-skin-cancer-diagnosis.
Evans, H., & Shapiro, M. (1997). Viruses. In: Manual of Techniques in Insect Pathology (pp. 17–53). Elsevier.
Fauser, B. (2019). Towards the global coverage of a united registry of IVF outcomes. Reprod Biomed Online № 2(38).
Frenzel, A., Hust, M., & Schirrmann, Th. (2013). Expression of recombinant antibodies. Frontiers in Immunology, 4, 217.
Fukuyama F. (2002). Our post-human future: consequences of the bio-technology revolution. Farrar, Straus, and Giroux, New York.
Gibbs, R. A. (2020). The human genome project changed everything. Nature Reviews Genetics, 21(10), 575–576.
Goecks, J., Jalili, V., Heiser, L. M., & Gray, J. W. (2020). How machine learning will transform biomedicine. Cell, 181(1), 92–101.
Gongalsky, M. B., Osminkina, L. A., Pereira, A., Manankov, A. A., Fedorenko, A. A., Vasiliev, A. N., Solovyev, V. V., et al. (2016). Laser-synthesized oxide-passivated bright si quantum dots for bioimaging. Scientific Reports, 6(1), 24732. https://doi.org/10.1038/srep24732
Grinin, L. (2020). How can COVID-19 change geopolitics and economy? Journal of Globalization Studies, 11(2), 121–134.
Grinin, A., & Grinin, L. (2020). Crossing the threshold of cyborgization. Journal of Big History, 4(3), 54–65.
Grinin, A. L., & Grinin, L. E. (2021) Are we on the threshold of cyborgization? In L. E. Grinin, I. V. Ilyin, & A. V. Korotayev (eds.), Globalistics and Globalization Studies: Current and Future Trends in the Big History Perspective (pp. 355–368). Volgograd: ‘Uchitel’ Publishing House.
Grinin, A. L., & Grinin, L. E. (2022). Cyborgization: to Be or not to Be? In L. E. , Grinin & A. V. Korotayev (eds.), Evolution: Trajectories of Social Evolution (pp. 187–202). Volgograd: ‘Uchitel’ Publishing House.
Grinin, L., Grinin, A., & Korotayev, A. (2022). COVID-19 pandemic as a trigger for the acceleration of the cybernetic revolution, transition from E-Government to E-State, and change in social relations. Technological Forecasting and Social Change, 175, 1–15. https://doi.org/10.1016/j.techfore.2021.121348
Gritsenko, D., & Maleva, Y. (2023). Kletochnoye vremya: rossiyskiye uchenyye izobreli «protez» dlya pecheni. Kak zastavit’ sobstvennyye kletki organizma vosstanovit’ bol’noy organ.. Izvestiya 09.08.2023. https://iz.ru/1556127/denis-gritcenko-iuliia-maleva/kletochnoe-vremia-rossiiskie-uchenye-izobreli-protez-dlia-pecheni
Harney, A. (2018). China orders investigation after scientist claims first gene-edited babies. Reuters, sec. Healthcare & Pharma. https://www.reuters.com/article/us-health-china-babies-genes-idUSKCN1NV19T.
Hsieh, T.-Ch, Bar-Haim, A., Moosa, Sh., Ehmke, N., Gripp, K. W., Pantel, J. T., & Danyel, M. et al. (2022). GestaltMatcher facilitates rare disease matching using facial phenotype descriptors. Nature Genetics, 54(3), 349–57. https://doi.org/10.1038/s41588-021-01010-x
Hussain, M. (2021). The changing dynamics of liberal international order: Covid-19 and its global implications. Journal of Globalization Studies, 12(2), 143–156.
Hussein, S. (2022). Spinal implant enables paralyzed man with severed spine to walk again: ScienceAlert. ScienceAlert. https://www.sciencealert.com/implant-allows-man-with-severed-spine-to-walk-again.
Illich, I. (1975). The medicalization of life. Journal of Medical Ethics, 1(2), 73–77.
Irshad, S. M. (2020). COVID-19 and Global ‘At-Risk Community’: From benefit-sharing to risk-sharing of economic crisis. Journal of Globalization Studies, 11(2), 135–145.
ISAPS. (2021). Aesthetic plastic surgery national databank. STATISTICS 2020–2021. https://cdn.theaestheticsociety.org/media/statistics/2021-TheAestheticSocietyStatistics.pdf
Jasiński, A. M., & Bąkowska, A. M. (2020). Globalization and life satisfaction of the polish population. Before and during the COVID-19 Pandemic. Journal of Globalization Studies, 11(2), 146–155.
Jiang, F., Xiao, Z., Wang, T., Wang, J., Bie, L., Saleh, L., Frey, K., Zhang, L., & Wang, J. (2022). Rapid and sensitive multiplex detection of COVID-19 antigens and antibody using electrochemical immunosensor-/aptasensor-enabled biochips. Chemical Communications, 58(52), 7285–7288. https://doi.org/10.1039/D2CC01598F
Kakkar, S. (2021). The outbreak of sars-cov-2 (Covid-19): Impact on international tourism. Journal of Globalization Studies, 12(1), 145–158.
Kelly, S. (2020). Robotic surgeries surge to 15% of All procedures, despite limited evidence. MedTech Dive. https://www.medtechdive.com/news/robotic-surgeries-surge-to-15-of-all-procedures-despite-limited-evidence/570370/.
Kondratieff, V. B. (2011). Globalnaya farmatsevticheskaya promyshlennost. Perspektivy, July 18. http://www.perspektivy.info/book/globalnaja_farmacevticheskaja_promyshlennost_2011-07-18.htm.
Konnikova, M. R., Cherkasova, O. P., Nazarov, M. M., Vrazhnov, D. A., Kistenev, Y. V., Titov, S. E., Kopeikina, E. V., Shevchenko, S. P., & Shkurinov, A. P. (2021). Malignant and benign thyroid nodule differentiation through the analysis of blood plasma with terahertz spectroscopy. Biomedical Optics Express, 12(2), 1020–1035. https://doi.org/10.1364/BOE.412715
Kostina, G. (2013). Pokoleniye R. Ekspert, 63–65.
Kurzweil, R. (1999). Age of spiritual machines. Penguin Books.
Kurzweil, R. (2005). The singularity is near: When humans transcend biology. New York, NY: Viking Penguin.
Lagasse, E., & Levin, M. (2023). Future medicine: From molecular pathways to the collective intelligence of the body. Trends in Molecular Medicine, 29(9), 687–710. https://doi.org/10.1016/j.molmed.2023.06.007
Landman, B. (2023). Human cadaver tissue could be the secret to looking younger. NYPost 19.06.2023. https://nypost.com/2023/06/19/human-cadaver-tissue-could-be-the-secret-to-looking-younger/
Leigh, J. P., Tancredi, D., Jerant, A., & Kravitz, R. L. (2010). Physician wages across specialties: Informing the physician reimbursement debate. Archives of Internal Medicine, 170(19), 1728–1734.
Lepuschitz, R. (2010). BCIS: The new ontological dimension of cyberspace. Masaryk UJL & Tech., 4, 147.
Lwoff, A., Horne R., & Tournier, P. (1962). A system of viruses. In: Cold Spring Harbor Symposia on Quantitative Biology, 27, 51–55. Cold Spring Harbor Laboratory Press.
MacKimm, D. (2022). Unborn baby undergoes heart surgery in womb after doctors detect tumor. ABC4 Utah (blog), https://www.abc4.com/news/unborn-baby-undergoes-heart-surgery-in-womb-after-doctors-detect-tumor/.
Marchione, M. (2017). AP exclusive: US scientists try 1st gene editing in the body. AP NEWS, https://apnews.com/article/technology-business-health-genetic-frontiers-science--4ae98919b52e43d8a8960e0e260feb0a.
Marescaux, J., Dallemagne, B., Perretta, S., Wattiez, A., Mutter, D., & Coumaros, D. (2007). Surgery without scars: report of transluminal cholecystectomy in a human being. Archives of Surgery, 142(9), 823–826. https://doi.org/10.1001/archsurg.142.9.823
Martyushev-Poklad, A. (2015). Chto proiskhodit s meditsinoy: protokol vskrytiya (1). Aftershock. URL: http://aftershock.su/?q=node/300253.
McGee, G. (1997). The perfect baby: A pragmatic approach to genetics. Lanham, Md.: Rowman and Littlefield.
McKie, R. (2015). German woman aged 65 gives birth to quadruplets after IVF treatment. The Guardian, May 23. URL: http://www.theguardian.com/world/2015/may/23/annegret-raunigk-german-woman-birth-quadruplets-aged-65.
Medical Error Statistics. (2022). Medical error statistics [2020]: Deaths/Year & Malpractice Rates. My Medical Score. Accessed September 8, 2022. https://mymedicalscore.com/medical-error-statistics/.
Minger, S. L. (2006). Regenerative medicine. Regenerative Medicine, 1(1), 1–2.
Mirsky, M. B. (2010). Istoriya meditsiny i khirurgii. GEOTAR-Media.
Moskalev, A. A. (2018). 120 let zhizni—tol’ko nachalo. Kak pobedit’ stareniye? Moskva: Eksmo.
Moynihan, R., Doran, E., & Henry, D. (2008). Disease mongering is now part of the global health debate. PLoS Medicine, 5(5), e106. https://doi.org/10.1371/journal.pmed.0050106
Mukherjee, S. (2022). The song of the cell: An exploration of medicine and the new human. Simon and Schuster.
Murray, C. J. L., & Lopez, A. D. (2013). Measuring the global burden of disease. The New England Journal of Medicine, 2013(369), 448–457. https://doi.org/10.1056/NEJMra1201534
Murray, C. J. L., Salomon, J. A., Colin, D. M., & Lopez, A. D. (Eds.). (2002). Summary measures of population health: Concepts, ethics. World Health Organization.
Murray, C. J. L., Ezzati, M., Flaxman, A. D., et al. (2012). GBD 2010: Design, definitions, and metrics. Lancet, 2012(380), 2063–2066. https://doi.org/10.1016/S0140-6736(12)61899-6
NIH—National Institutes of Health. (2021). Annual report to the nation: Rapid decrease in lung cancer and melanoma deaths lead overall continued decline in cancer death rate. https://www.nih.gov/news-events/news-releases/annual-report-nation-rapid-decrease-lung-cancer-melanoma-deaths-lead-overall-continued-decline-cancer-death-rate.
Njagi, P., Groot, W., Arsenijevic, J., Dyer, S., Mburu, G., & Kiarie, J. (2023). Financial costs of assisted reproductive technology for patients in low-and middle-income countries: a systematic review. Human Reproduction Open (2), hoad007.
NCHS—National Center for Health Statistics. (2021). Drug overdose deaths in the U.S. Top 100,000 Annually for Immediate Release: November 17, 2021. https://www.cdc.gov/nchs/pressroom/nchs_press_releases/2021/20211117.htm
Null, G., Dean, C., Feldman, M., Rasio, D., & Smith, D. (2004). Death by Medicine. URL: http://www.whale.to/a/null9.html.
OECD. (2022). Health expenditure and financing. https://stats.oecd.org/Index.aspx?DataSetCode=SHA.
Palmisano, M. E., Gaffga, A. M., Daigle, J., Brinkman, J., Mire, K., Lenczyk, K., Martin, D. H., & Hagensee, M. E. (2003). Detection of human papillomavirus DNA in self-administered vaginal swabs as compared to cervical swabs. International Journal of STD & AIDS, 14(8), 560–567. https://doi.org/10.1258/095646203767869183
Peercy, P. S. (2000). The drive to miniaturization. Nature, 406(6799), 1023–1026.
Petrov S. V. (2014). (ed.) Obshchaya khirurgiya. Manual. GEOTAR-Media, Moscow.
Pile, D. (2013). Artificial antibodies. Nature Photonics, 7(1), 3–3. https://doi.org/10.1038/nphoton.2012.354
Pinkerton, S. (2013). The pros and cons of robotic surgery. Wall Street Journal, November 17. https://online.wsj.com/article/SB10001424052702304655104579163430371597334.html.
Prillaman, Mc. K. (2022). Prehistoric Child’s amputation is oldest surgery of its kind. Nature, 609(7927), 453–454. https://doi.org/10.1038/d41586-022-02849-8
Pylyshyn, Z. W. (2003). Seeing and visualizing: It’s not what you think. Mit Press.
Raff, M. (1998). Cell suicide for beginners. Nature, 396, 119–122.
Ridley, M. (1996). The origin of virtue. New York, NY: Viking.
Ren, X., Ellis, B. W., Ronan, G., Blood, S. R., DeShetler, C., Senapati, S., March, K. L., et al. (2021). A multiplexed ion-exchange membrane-based MiRNA (MIX·miR) detection platform for rapid diagnosis of myocardial infarction. Lab on a Chip, 21(20), 3876–3887. https://doi.org/10.1039/D1LC00685A
Romanis, E. Ch. (2018). Artificial womb technology and the frontiers of human reproduction: Conceptual differences and potential implications. Journal of Medical Ethics, 44(11), 751–55.
Rybalkina, M. (2005). Nanotekhnologii dlya vsekh. Nanotechnology News Network.
Saigitov, R. (2015). Velikaya stagnatsiya meditsiny. Lenta.ru, April 11. http://lenta.ru/articles/2015/04/11/biotech/.
Saijo, H., Kanno, Y., Mori, Y., Suzuki, S., Ohkubo, K., Chikazu, D., Yonehara, Y., Chung, U.-I., & Takato, T. (2011). A novel method for designing and fabricating custom-made artificial bones. International Journal of Oral and Maxillofacial Surgery, 40(9), 955–960.
Schirhagl, R., Qian, J., & Dickert, F. L. (2012). Immunosensing with artificial antibodies in organic solvents or complex matrices. Sensors & Actuators: b. Chemical, 173, 585–590.
Schneider, S. (2009). Science fiction and philosophy: From time travel to superintelligence, 1st Edn Malden, MA: Wiley-Blackwell. ?
Sciencedaily. (2018). More than 8 million babies born from IVF since the world’s first in 1978. https://www.sciencedaily.com/releases/2018/07/180703084127.htm.
Seifabadi, M. S., & Dolatabadi, A. B. (2022). Covid-19, Globalization and strengthening authoritarianism in the middle east. Journal of Globalization Studies, 13(1), 135–157.
Siemionow, M. (2017). The decade of face transplant outcomes. JOurnal of Materials Science: Materials in Medicine, 28(5), 1–5.
Simon, S. (2020). Facts & figures 2020 reports largest one-year drop in cancer mortality. https://www.cancer.org/latest-news/facts-and-figures-2020.html.
Simonstein, F. (2006). Artificial reproduction technologies (RTs)—all the way to the artificial womb? Medicine, Health Care and Philosophy, 9(3), 359–365.
Sindyashkina, E. N. (2022). Healthy life expectancy in the context of the united nations decade of healthy ageing. Analysis and Forecasting. IMEMO Journal, 2022(1), 40–53.
Singh, S., Tank, N. K., Dwiwedi, P., Charan, J., Kaur, R., Sidhu, P., & Chugh, V. K. (2018). Monoclonal antibodies: A review. Current Clinical Pharmacology, 13(2), 85–99. https://doi.org/10.2174/1574884712666170809124728
Slagboom, P. ЕS., Droog, S., & Boomsma, D. I. (1994). Genetic determination of telomere size in humans: A twin study of three age groups. American Journal of Human Genetics, 55, 876–882.
Smith, M. W. (1979). A guide to the delineation of medical care regions, medical trade areas, and hospital service areas. Public Health Reports., 94(3), 248.
Solé, R., & Elena, S. F. (2018). Viruses as complex adaptive systems. In: Viruses as Complex Adaptive Systems. Princeton University Press.
Statista. (2022a). Total drug prescriptions dispensed U.S. 2009–2021. Statista. https://www.statista.com/statistics/238702/us-total-medical-prescriptions-issued/.
Statista. (2022b). Pharmaceutical market revenue forecast 2012–2022. Statista. https://www.statista.com/statistics/817562/revenue-forecast-for-global-pharma-market/.
Stein, L. D. (2004). Human genome: End of the beginning. Nature, 431(7011), 915–916.
Strategy of Development. (2013). Strategiya razvitiya meditsinskoy nauki v Rossiyskoy Federatsii na period do 2025 goda. http://rosminzdrav.ru/health/62/Strategiya_razvitiya_meditcinskoj_nauki.pdf.
Sung, H., Ferlay, J., Siegel, R. L., Laversanne, M., Soerjomataram, I., Jemal, A., & Bray, F. (2021). Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 71(3), 209–249. https://doi.org/10.3322/caac.21660.
Tang, D., & Kang, R. (2022). Glimmers of hope for targeting oncogenic KRAS-G12D. Cancer Gene Therapy, 1–3.
Taylor, R. H. (1997). Robots as surgical assistants: Where we are, wither we are tending, and how to get there. artificial intelligence in medicine. Lecture Notes in Computer Science 1211: 1–11. Springer Berlin Heidelberg. URL: http://link.sprin ger.com/chapter/https://doi.org/10.1007/BFb0029430.
Toren, P., Smolka, M., Haase, A., Palfinger, U., Nees, D., Ruttloff, S., Kuna, L., et al. (2020). High-throughput roll-to-roll production of polymer biochips for multiplexed DNA detection in point-of-care diagnostics. Lab on a Chip, 20(22), 4106–4117. https://doi.org/10.1039/D0LC00751J
Wagner, V., Dullaart, A., Bock, A.-K., & Zweck, A. (2006). The emerging nanomedicine landscape. Nature Biotechnology, 24(10), 1211–1217.
Wang, H., Dwyer-Lindgren, L., Lofgren, K. T., et al. (2012). Age-specific and sex-specific mortality in 187 countries, 1970–2010: A systematic analysis for the global burden of disease study 2010. Lancet, 380, 2071–2094. https://doi.org/10.1016/S0140-6736(12)61719-X
Wasden, Ch., & Williams, B. (2012). Owning the disease: A new transformational business model for healthcare. http://pwc.com/ie/pubs/2012_new_transformational_business_model_for_healthcare.pdf.
Werner, K. M., & Mercurio, M. R. (2021). Ethical considerations in the use of artificial womb/placenta technology. Seminars in Perinatology, 151521. Elsevier,
WHO. (2020). The top 10 causes of death. https://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death.
WHO. (2023a). Disability factsheet 2023. WHO. https://www.who.int/news-room/fact-sheets/detail/disability-and-health#:~:text=An%20estimated%201.3%20billion%20people%20%E2%80%93%20or%2016%25%20of%20the%20global,experience%20a%20significant%20disability%20today.
WHO. (2023b). WHO mortality database. Geneva: WHO. https://platform.who.int/mortality
Widdowson, M. (2021). From Covid-19 to zero-gravity: Complex crises and production revolutions. Journal of Globalization Studies, 12(1), 117–144.
Williams, S. (2014). 3 Pharma giants growing significantly faster than Glax-oSmithKline PLC. http://www.fool.com/investing/general/2014/12/26/3-pharma-giants-growing-significantly-faster-than.aspx. Date accessed: 2.01.2015.
Willyard, C. (2016). Cancer therapy: An evolved approach. Scientific American https://www.scientificamerican.com/article/cancer-therapy-an-evolved-approach/.
Woollett, G. R. (2012). Innovation in Biotechnology: Current and future states. Clinical Pharmacology and Therapeutics, 91(1), 17–20.
World Bank. (2011). New world report shows more than 1 billion people with disabilities face substantial barriers in their daily lives. https://www.who.int/mediacentre/news/releases/2011/disabilities_20110609/en/.
Xu, N., Ye, X., Wei, D., Zhong, J., Chen, Y., Xu, G., & He, D. (2014). 3D artificial bones for bone repair prepared by computed tomography-guided fused deposition modeling for bone repair. ACS Applied Materials & Interfaces, 6(17), 14952–63
Yang, A., Xuan, R., & Murrell, D. F. (2019). A new indirect immunofluorescence BIOCHIP method for the serological diagnosis of bullous pemphigoid: A review of literature. Australasian Journal of Dermatology, 60(3), e173–e177. https://doi.org/10.1111/ajd.13034
Yong, Ed. (2014). Cancer biomarkers: Written in blood. Nature, 511(7511), 524–26.https://doi.org/10.1038/511524a
Yu, J., & Hu, S. (2021). On the ultimate finishing line of the human genome project. The Innovation, 2(3).
Yudin, B. G. (2008). Meditsina i konstruirovaniye cheloveka. Znanie, ponimanie, umenie, 1, 12–20. http://cyberleninka.ru/article/n/meditsina-i-konstruirovanie-cheloveka.
Zhokhova, A. (2011). My sdelayem vam krasivo. Forbes, June 3. http://m.forbes.ru/article.php?id=69681.
Acknowledgements
This chapter has been prepared with support by the Russian Science Foundation (Project No. 23-11-00160).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
Copyright information
© 2024 The Author(s), under exclusive license to Springer Nature Switzerland AG
About this chapter
Cite this chapter
Grinin, L., Grinin, A., Korotayev, A. (2024). Medicine and the Cybernetic Revolution: On the Way to Control Over the Human Body. In: Cybernetic Revolution and Global Aging. World-Systems Evolution and Global Futures. Springer, Cham. https://doi.org/10.1007/978-3-031-56764-3_8
Download citation
DOI: https://doi.org/10.1007/978-3-031-56764-3_8
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-031-56763-6
Online ISBN: 978-3-031-56764-3
eBook Packages: Social SciencesSocial Sciences (R0)