Abstract
Aerosols are microscopic solid or liquid particles suspended in the air people breathe. Despite their tiny size, aerosols are extremely important to human health and the planet’s climate. Aerosols in the atmosphere come from both manmade and natural sources. Their diameters in the atmosphere range from a few nanometers to micrometers, depending on where they come from and what kind they are. Numerous respiratory viruses can spread through contact and droplet transmission. The World Health Organization (WHO) has warned that the SARS-CoV-2 virus, known as COVID-19, may spread via airborne transmission. According to growing epidemiological evidence, viral aerosol is an important mode of transmission for coronavirus and influenza due to its high infectiousness and propensity for rapid spread. Another crucial topic of study is how bioaerosols contribute to the current COVID-19 pandemic’s transmission. Evidence suggests that, in favorable circumstances, aerosols aid in transmitting COVID-19. When a person with the virus exhales microscopic particles that hang in the air without much dilution, this could result in short-range aerosol transmission. If enough are breathed in by a susceptible person, they could spread the infection. Aerosol particles dispersing away from the diseased person can also expose them. At distances more than a few feet, COVID-19 can be spread by inhaling the virus in the air. An entire room or indoor space can get contaminated with particles from an ill person. According to popular belief, SARS-CoV-2 spreads via droplets released during ill individuals’ coughing, sneezing, talking, or exhaling. Some droplets fall on surrounding floors or surfaces because they are too heavy to stay in the air.
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References
Anderson, E. L., Turnham, P., Griffin, J. R., & Clarke, C. C. (2020). Consideration of the aerosol transmission for COVID-19 and public health. Risk Analysis, 40, 902–907. https://doi.org/10.1111/risa.13500
Asadi, S., Bouvier, N., Wexler, A. S., & Ristenpart, W. D. (2020). The coronavirus pandemic and aerosols: Does COVID-19 transmit via expiratory particles? Aerosol Science and Technology, 54, 635–638.
Bai, Y., Yao, L., Wei, T., et al. (2020). Presumed asymptomatic carrier transmission of COVID-19. Journal of the American Medical Association, 323, 1406–1407.
Bao, L., Gao, H., Deng, W., Lv, Q., Yu, H., Liu, M., et al. (2020). Transmission of SARS-CoV-2 via close contact and respiratory droplets among hACE2 mice. The Journal of Infectious Diseases, 222, 551–555. https://doi.org/10.1093/infdis/jiaa281
Baron, P. A., & Willeke, K. (2001). Aerosol measurement principles, techniques and applications (2nd ed.). Wiley.
Blessy, A., John Paul, J., Gautam, S., et al. (2023). IoT-based air quality monitoring in hair salons: Screening of hazardous air pollutants based on personal exposure and health risk assessment. Water, Air, and Soil Pollution, 234, 336. https://doi.org/10.1007/s11270-023-06350-4
Boone, S. A., & Gerba, C. P. (2007). Significance of fomites in the spread of respiratory and enteric viral disease. Applied and Environmental Microbiology, 73(6), 1687–1696. https://doi.org/10.1128/AEM.02051-06. Epub 2007 Jan 12. PMID: 17220247; PMCID: PMC1828811.
Borak, J. (2020). Airborne transmission of COVID-19. Occupational Medicine, 370, 303–304. https://doi.org/10.1093/occmed/kqaa080
Bourouiba, L. (2020). Turbulent gas clouds and respiratory pathogen emissions: Potential implications for reducing transmission of COVID-19. Journal of the American Medical Association. https://doi.org/10.1001/jama.2020.4756
Brankston, G., Gitterman, L., Hirji, Z., Lemieux, C., & Gardam, M. (2007). Transmission of influenza A in human beings. The Lancet Infectious Diseases, 7, 257–265. https://doi.org/10.1016/S14733099(07)70029-4
Buonanno, G., Stabile, L., & Morawska, L. (2020). Estimation of airborne viral emission: Quanta emission rate of SARS-CoV-2 for infection risk assessment. Environment International, 141, 105794. https://doi.org/10.1016/j.envint.2020.105794
Chen, W., Zhang, N., Wei, J., Yen, H. L., & Li, Y. (2020). Short-range airborne route dominates exposure of respiratory infection during close contact. Building and Environment, 176, 106850. https://doi.org/10.1016/j.buildenv.2020.106859
Coronaviridae Study Group. (2020). Coronaviridae Study Group of the International Committee on Taxonomy of Viruses. The species severe acute respiratory syndrome- related coronavirus: Classifying 2019-nCoV and naming it SARS-CoV-2. Nature Microbiology, 5, 536–544.
Cox, C. S. (1995). Physical aspects of bioaerosols particles. In C. S. Cox & C. M. Wathes (Eds.), Bioaerosols handbook (pp. 15–25). Lewis Publishers.
Deng, S. Q., & Peng, H. J. (2020). Characteristics of and public health responses to the coronavirus disease 2019 outbreak in China. Journal of Clinical Medicine, 9, 575.
Gautam, S. (2020a). COVID-19: Air pollution remains low as people stay at home. Air Quality, Atmosphere and Health, 13, 853–857. https://doi.org/10.1007/s11869-020-00842-6
Gautam, S. (2020b). The influence of COVID-19 on air quality in India: A boon or inutile. Bulletin of Environmental Contamination and Toxicology, 104, 724–726. https://doi.org/10.1007/s00128-020-02877-y
Gralton, J., Tovey, E., McLaws, M. L., & Rawlinson, W. D. (2011). The role of particle size in aerosolised pathogen transmission: A review. The Journal of Infection, 62, 1–13.
Grayson, S. A., Griffiths, P. S., Perez, M. K., & Piedimonte, G. (2016). Detection of airborne respiratory syncytial virus in a pediatric acute care clinic. Pediatric Pulmonology, 52, 684–688. https://doi.org/10.1016/j.jinf.2010.11.010
Halloran, S. K., Wexler, A. S., & Ristenpart, W. D. (2012). A comprehensive breath plume model for disease transmission via expiratory aerosols. PLoS One, 7, e0037088. https://doi.org/10.1371/journal.pone.0037088
Han, Q., Lin, Q., Jin, S., & You, L. (2020). Coronavirus 2019-nCoV: A brief perspective from the front line. The Journal of Infection, 80, 373–377.
Hinds, W. C. (1999). Aerosol technology: Properties, behavior, and measurement of AirBorne particles (2nd ed.). Wiley.
Hu, B., Guo, H., Zhou, P., et al. (2021). Characteristics of SARS-CoV-2 and COVID-19. Nature Reviews. Microbiology, 19, 141–154. https://doi.org/10.1038/s41579-020-00459-7
Huang, Y., Yang, C., Xu, X. F., Xu, W., & Liu, S. W. (2020). Structural and functional properties of SARS-CoV-2 spike protein: Potential antivirus drug development for COVID-19. Acta Pharmacologica Sinica, 41, 1141–1149.
Hui, D. S., et al. (2020). The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health—The latest 2019 novel coronavirus outbreak in Wuhan, China. International Journal of Infectious Diseases, 91, 264–266.
Jayaweera, M., Perera, H., Gunawardana, B., & Manatunge, J. (2020). Transmission of COVID-19 virus by droplets and aerosols: A critical review on the unresolved dichotomy. Environmental Research, 188, 109819. https://doi.org/10.1016/j.envres.2020.109819
Jiang, S., Du, L., & Shi, Z. (2020). An emerging coronavirus causing pneumonia outbreak in Wuhan, China: Calling for developing therapeutic and prophylactic strategies. Emerging Microbes & Infections, 9, 275–277.
Jones, R. M. (2020). Relative contributions of transmission routes for COVID-19 among healthcare personnel providing patient care. Journal of Occupational and Environmental Hygiene, 17, 408–415. https://doi.org/10.1080/15459624.2020.1784427
Judson, S. D., & Munster, V. J. (2019). Nosocomial transmission of emerging viruses via aerosol-generating medical procedures. Viruses, 11, 940. https://doi.org/10.3390/v11100940
Killingley, B., & Nguyen-Van-Tam, J. (2013). Routes of influenza transmission. Influenza and Other Respiratory Viruses, 7, 42–51.
Konda, A., Prakash, A., Moss, G. A., Schmoldt, M., Grant, G. D., & Guha, S. (2020). Aerosol filtration efficiency of common fabrics used in respiratory cloth masks. ACS Nano, 14, 6339–6347. https://doi.org/10.1021/acsnano.0c03252
Kudryashova, O. B., Muravlev, E. V., Antonnikova, A. A., & Titov, S. S. (2021). Propagation of viral bioaerosols indoors. PLoS One, 16(1), e0244983. https://doi.org/10.1371/journal.pone.0244983. PMID: 33400714; PMCID: PMC7785217.
Kumar, P., & Morawska, L. (2019). Could fighting airborne transmission be the next line of defence against COVID-19 spread? City and Environment Interactions, 4, 100033. https://doi.org/10.1016/j.cacint.2020.100033
Kumar, R. P., Perumpully, S. J., Samuel, C., et al. (2023). Exposure and health: A progress update by evaluation and scientometric analysis. Stochastic Environmental Research and Risk Assessment, 37, 453–465. https://doi.org/10.1007/s00477-022-02313-z
Lewis, D. (2020). Is the coronavirus airborne? Experts can’t agree. Nature, 580, 175. https://doi.org/10.1038/d41586-020-00974-w
Liu, L., Wei, J., Li, Y., & Ooi, A. (2016). Evaporation and dispersion of respiratory droplets from coughing. Indoor Air, 27, 179–190. https://doi.org/10.1111/ina.12297
Loh, N. H. W., Tan, Y., Taculod, J., Gorospe, B., Teope, A. S., Somani, J., & Tan, A. Y. H. (2020). The impact of high-flow nasal cannula (HFNC) on coughing distance: Implications on its use during the novel coronavirus disease outbreak. Canadian Journal of Anesthesia, 1–2. https://doi.org/10.1007/s12630-020-01634-3
Long, Y., Hu, T., Liu, L., Chen, R., Guo, Q., Yang, L., Cheng, Y., Huang, J., & Du, L. (2020). Effectiveness of N95 respirators versus surgical masks against influenza: A systematic review and meta-analysis. Journal of Evidence-Based Medicine. https://doi.org/10.1111/jebm.12381
Marthi, B. (1994). Resuscitation of microbial bioaerosols. In B. Lighthart & A. J. Mohr (Eds.), Atmospheric microbial aerosols (pp. 192–225). Springer. https://doi.org/10.1007/978-1-4684-6438-2_7
McCluskey, R., Sandin, R., & Greene, J. (1996). Detection of airborne cytomegalovirus in hospital rooms of immuno-compromised patients. Journal of Virological Methods, 56, 115–118. https://doi.org/10.1016/0166-0934(95)01955-3
Morawska, L. (2006). Droplet fate in indoor environments, or can we prevent the spread of infection. Indoor Air, 16, 335–347.
Morawska, L., & Cao, J. (2020). Airborne transmission of SARS-CoV-2: The world should face the reality. Environment International, 139, 105730. https://doi.org/10.1016/j.envint.2020.105730
Morawska, L., & Milton, D. K. (2020). It is time to address airborne transmission of coronavirus disease 2019 (COVID-19). Clinical Infectious Diseases, 71(9), 2311–2313. https://doi.org/10.1093/cid/ciaa939
Morawska, L., Tang, J. W., Bahnfleth, W., Bluyssen, P. M., Boerstra, A., Buonanno, G., et al. (2020). How can airborne transmission of COVID-19 indoors be minimised? Environment International, 142, 105832. https://doi.org/10.1016/j.envint.2020.105832
Newman, S. (2009). Respiratory drug delivery. Essential theory and practice. RDD Online-VCU.
Nicas, M., Nazaroff, W. W., & Hubbard, A. (2005). Towards understanding the risk of secondary airborne infection: Emission of respirable pathogens. Journal of Occupational and Environmental Hygiene, 2, 143–154.
Prather, K. A., Marr, L. C., Schooley, R. T., McDiarmid, M. A., Wilson, M. E., & Milton, D. K. (2020). Airborne transmission of SARS-CoV-2. Science, 370, 303–304.
Ren, S. Y., Wang, W. B., Hao, Y. G., Zhang, H. R., Wang, Z. C., Chen, Y. L., et al. (2020). Stability and infectivity of coronaviruses in inanimate environments. World Journal of Clinical Cases, 8, 1391–1399. https://doi.org/10.12998/wjcc.v8.i8.1391
Schuit, M., Ratnesar-S, S., Yolitz, J., Williams, G., Weaver, W., Green, B., et al. (2020). Airborne SARS-CoV-2 is rapidly inactivated by simulated sunlight. The Journal of Infectious Diseases, 222, 564–571. https://doi.org/10.1093/infdis/jiaa334
Shiu, E. Y. C., Leung, N. H. L., & Cowling, B. J. (2019). Controversy around airborne versus droplet transmission of respiratory viruses: Implication for infection prevention. Current Opinion in Infectious Diseases, 32, 372–379. https://doi.org/10.1097/QCO.0000000000000563
Smither, S. J., Eastaugh, L. S., Findlay, J. S., & Lever, M. S. (2020). Experimental aerosol survival of SARS-CoV-2 in artificial saliva and tssue culture media at medium and high humidity. Emerging Microbes & Infections, 9, 1415–1417. https://doi.org/10.1080/22221751.2020.1777906
Sugano, N., Ando, W., & Fukushima, W. (2020). Cluster of SARS-CoV-2 infections linked to music clubs in Osaka, Japan: Asymptomatically infected persons can transmit the virus as soon as 2 days after infection. The Journal of Infectious Diseases, 222, 1635–1640. https://doi.org/10.1093/infdis/jiaa542
Tellier, R. (2006). Review of aerosol transmission of influenza A virus. Emerging Infectious Diseases, 12, 1657–1662. https://doi.org/10.3201/eid1211.060426
Tellier, R. (2009). Aerosol transmission of influenza A virus: A review of new studies. Journal of The Royal Society Interface, 6, S783–S790. https://doi.org/10.1098/rsif.2009.0302.focus
Thomas, R. J. (2013). Particle size and pathogenicity in the respiratory tract. Virulence, 4, 847–858. https://doi.org/10.4161/viru.27172
Van Doremalen, N., Bushmaker, T., Morris, D. H., Holbrook, M. G., Gamble, A., Williamson, B. N., et al. (2020). Aerosol and surface stability of SARS-CoV-2 as compared with SARS-CoV-1. The New England Journal of Medicine, 382, 1564–1567.
Vuorinen, V., Aarnio, M., Alava, M., Alopaeus, V., Atanasova, N., Auvinen, M., et al. (2020). Modelling aerosol transport and virus exposure with numerical simulations in relation to SARS-CoV-2 transmission by inhalation indoors. Safety Science, 130, 104866. https://doi.org/10.1016/j.ssci.2020.104866
Wang, J., & Du, G. (2020). COVID-19 may transmit through aerosol. Irish Journal of Medical Science, 1–2. https://doi.org/10.1007/s11845-020-02218-2
Weber, T. P., & Stilianakis, N. I. (2008). Inactivation of influenza A viruses in the environment and modes of transmission: A critical review. The Journal of Infection, 57, 361–373.
Wei, J. J., & Li, Y. G. (2016). Airborne spread of infectious agents in the indoor environment. American Journal of Infection Control, 44, S102–S108. https://doi.org/10.1016/j.ajic.2016.06.003
WHO. (2014). Infection prevention and control of epidemic-and pandemic-prone acute respiratory infections in health care. https://www.who.int/publications/i/item/infection-prevention-and-control-of-epidemic-and-pandemic-prone-acute-respiratory-infections-in-health-care. Accessed 6 Sept 2023.
WHO. (2020a). Coronavirus disease 2019 (COVID-19) (Situation report – 51). World Health Organization. https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200311-sitrep-51-covid-19.pdf?sfvrsn=1ba62e57_10
WHO. (2020b). Modes of transmission of virus causing COVID-19: Implications for infection prevention and control (IPC) precaution recommendations and includes new scientific evidence available on transmission of SARS-CoV-2, the virus that causes COVID-19. Scientific Brief.
WHO. (2020c). Advice on the use of masks in the context of COVID-19. Interim guidance. World Health Organization. Available at https://www.who.int/publications/i/item/advice-on-the-use-of-masks-in-the-community-during-home-care-and-in-healthcare-settings-in-the-context-of-the-novel-coronavirus-(2019-ncov)-outbreak
Wu, Z., & McGoogan, J. M. (2020). Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: Summary of a report of 72314 cases from the Chinese Center for Disease Control and Prevention. The Journal of the American Medical Association, 323, 1239–1242.
Wu, J. T., Leung, K., & Leung, G. M. (2020). Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: A modelling study. Lancet, 395, 689–697.
Xie, X., Li, Y., Chwang, A. T., Ho, P. L., & Seto, W. H. (2007). How far droplets can move in indoor environments–revisiting the Wells evaporation-falling curve. Indoor Air, 17, 211–225. https://doi.org/10.1111/j.1600-0668.2007.00469.x
Zhu, Y., Xie, J., Huang, F., & Cao, L. (2020). Association between short-term exposure to air pollution and COVID-19 infection: Evidence from China. Science of the Total Environment, 727, 138704. https://doi.org/10.1016/j.scitotenv.2020.138704
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Srivastava, N. (2024). Review of the Role of Aerosols in the Spread of COVID-19. In: Gautam, S., Kumar, R.P., Samuel, C. (eds) Aerosol Optical Depth and Precipitation. Springer, Cham. https://doi.org/10.1007/978-3-031-55836-8_10
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