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Maternal Vitamin D Levels During Gestation and Impact on Offspring’s Risk of Non-communicable Diseases in Adulthood

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Lipophilic Vitamins in Health and Disease

Part of the book series: Advances in Biochemistry in Health and Disease ((ABHD,volume 28))

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Abstract

Low vitamin D levels have been linked to conditions, including cardiovascular disease, certain malignancies, dementia, depression, diabetes, adverse pregnancy outcomes, and autoimmune diseases. Although vitamin D deficiency is a worldwide issue, it deserves specific attention in pregnant and nursing mothers due to the potential for unfavorable maternal–fetal outcomes. Vitamin D deficiency is increasingly prevalent among women of reproductive age and has been associated with gestational hypertension, preterm birth, and poorer offspring health. This chapter focuses on Vitamin D deficiency during gestation and its adverse effects on the fetal growth of neonates, during adolescence and adulthood of offspring. The role of epigenetic maternal–fetal adaptation mechanisms and vitamin D metabolism in the development of metabolic diseases is also explored.

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Authors and Affiliations

  1. Department of Medical Biotechnology, Gujarat Biotechnology University, Gandhinagar, Gujarat, 382355, India

    Rohini Ravindran Nair & Surya Ramachandran

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  1. Rohini Ravindran Nair
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  2. Surya Ramachandran
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Correspondence to Surya Ramachandran .

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  1. Asper Clinical Research Institute, St. Boniface Hospital, Winnipeg, MB, Canada

    Paramjit S. Tappia

  2. California State University Los Angeles, Los Angeles, CA, USA

    Anureet K. Shah

  3. Institute of Cardiovascular Science, St. Boniface Hospital, Winnipeg, MB, Canada

    Naranjan S. Dhalla

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Nair, R.R., Ramachandran, S. (2024). Maternal Vitamin D Levels During Gestation and Impact on Offspring’s Risk of Non-communicable Diseases in Adulthood. In: Tappia, P.S., Shah, A.K., Dhalla, N.S. (eds) Lipophilic Vitamins in Health and Disease. Advances in Biochemistry in Health and Disease, vol 28. Springer, Cham. https://doi.org/10.1007/978-3-031-55489-6_17

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