Abstract
Here we begin to delve into the heart of the book, deep brain stimulation and some of the mysteries that continue to confound the field of neuromodulation. Topics covered include: history of DBS, which patients are good candidates for this procedure, different options available to patients, the options surgeons have for electrode placement, and when patients should consider getting DBS.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Notes
- 1.
Wong JK, Mayberg HS, Wang DD, Richardson RM, Halpern CH, Krinke L, Arlotti M, Rossi L, Priori A, Marceglia S, Gilron R, Cavanagh JF, Judy JW, Miocinovic S, Devergnas AD, Sillitoe RV, Cernera S, Oehrn CR, Gunduz A, Goodman WK, Petersen EA, Bronte-Stewart H, Raike RS, Malekmohammadi M, Greene D, Heiden P, Tan H, Volkmann J, Voon V, Li L, Sah P, Coyne T, Silburn PA, Kubu CS, Wexler A, Chandler J, Provenza NR, Heilbronner SR, Luciano MS, Rozell CJ, Fox MD, de Hemptinne C, Henderson JM, Sheth SA, Okun MS. Proceedings of the 10th annual deep brain stimulation think tank: Advances in cutting edge technologies, artificial intelligence, neuromodulation, neuroethics, interventional psychiatry, and women in neuromodulation. Front Hum Neurosci. 2023;16:1084782.
- 2.
Benabid AL, Pollak P, Louveau A, Henry S, de Rougemont J. Combined (thalamotomy and stimulation) stereotactic surgery of the VIM thalamic nucleus for bilateral Parkinson disease. Appl Neurophysiol. 1987;50:344-6.
- 3.
Largely underrecognized French physicist and neuroscientist, an extraordinary example of the challenges of being a woman in neuroscience, years before the Nobel laureate Levi Rita Montalcini.
- 4.
Mundinger F. Neue stereotaktisch-funktionelle Behandlungsmethode des Torticollis spasmodicus mit Hirnstimulatoren [New stereotactic treatment of spasmodic torticollis with a brain stimulation system (author’s transl)]. Med Klin. 1977;72:1982-6.
- 5.
Brice J, McLellan L. Suppression of intention tremor by contingent deep-brain stimulation. Lancet. 1980;1:1221-2.
- 6.
One example is the pedunculopontine nucleus (a.k.a. PPN) which had been hyped up, but most researchers believe that it is not as effective in treating gait and balance as initially thought. Another is the Globus Pallidus pars enterna (GPe) which has been proposed as a target to improve bradykinesia, although preliminary results are not that encouraging. The Nucleus Basalis of Meynert has been stimulated with the aim to improve cognition in PD patients but, once again, the effects—if any—are very modest.
- 7.
EARLYSTIM Study Group. Neurostimulation for Parkinson’s disease with early motor complications. N Engl J Med. 2013;368:610–22.
- 8.
Restless leg syndrome, or simply RLS, is the uncontrollable urge to voluntary move the legs while in bed, thus causing insomnia.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2024 The Author(s), under exclusive license to Springer Nature Switzerland AG
About this chapter
Cite this chapter
Stecher, B., Fasano, A. (2024). To DBS or not to DBS…That Is the Question. In: Reprogramming the Brain. Springer, Cham. https://doi.org/10.1007/978-3-031-50399-3_3
Download citation
DOI: https://doi.org/10.1007/978-3-031-50399-3_3
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-031-50398-6
Online ISBN: 978-3-031-50399-3
eBook Packages: MedicineMedicine (R0)