Abstract
We begin this chapter by talking about the knowledge needed to understand a dying brain as it is dying. We talk about a few different branches of knowledge before settling on oscillopathies and make our case for why we think it is the most fundamental and the most actionable part of understanding who and what we are. Finally, we poll several experts in the field for their views on oscillopathies.
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Notes
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Kingwell K. Double setback for ASO trials in Huntington disease. Nat Rev Drug Discov. 2021;20:412–3.
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Dr. Starr is the Dolores Cakebread Professor of Neurological Surgery, at the University of California, San Francisco. Dr. Starr and UCSF neurologist Dr. Jill Ostrem are the directors of a multidisciplinary clinic for comprehensive care of patients with movement disorders. His NIH funded research addresses: brain network abnormalities underlying motor and nonmotor features of movement disorders; mechanisms of therapeutic DBS; the use of totally implantable neural interfaces for long term brain recording and aDBS.
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Dr. Little is an Assistant Professor of Neurology at UCSF. He’s an UK-trained neurologist who completed a PhD at Oxford University in experimental neurology, investigating personalized and responsive brain stimulation therapies for movement disorders.
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Dr. Gilron is the lead neuroscientist at Rune Labs (S. Francisco, CA, US) where he helps industry and academic partners develop personalized therapies for neurodegenerative disorders.
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Stecher, B., Fasano, A. (2024). Oscillopathies and You. In: Reprogramming the Brain. Springer, Cham. https://doi.org/10.1007/978-3-031-50399-3_15
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DOI: https://doi.org/10.1007/978-3-031-50399-3_15
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